Phylogenetic Analysis of G and P Genotypes of Bovine Group A Rotavirus Strains Isolated from Diarrheic Vietnam Cows in 2017 and 2018

• Published in: Animals (Basel) 2023-07, Vol.13 (14), p.2314
• Main Authors: Shin, Jihye, Park, Gyu-Nam, Choe, SeEun, Cha, Ra Mi, Kim, Ki-Sun, An, Byung-Hyun, Kim, Song Yi, Moon, Soo Hyun, Hyun, Bang-Hun, An, Dong-Jun
• Format: Article
• Language: English
• Subjects: Analysis; Beef cattle; BoRVA; Brief Report; Cattle; cow; Diarrhea; Feces; G-type; Genes; Genetic aspects; Genotype & phenotype; Livestock; P-type; phylogenetic tree; Phylogenetics; Phylogeny; Rotavirus; Viruses
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani13142314

This study aimed to investigate the genetic diversity of G- and P-type bovine RVAs (BoRVAs) prevalent in Vietnam. Between 2017 and 2018, the prevalence of BoRVAs detected in diarrhea samples from 8 regions was as low as 1.9% (11/582). The prevalence of the G-type was 45.5% for G6 and 18.2% for G10; however, 36.3% remain unidentified. Interestingly, all BoRVAs were investigated as P[11], and there was no diversity within this P-type. Geographically, the G6 and G10 types were not identified in any specific area; rather, they occurred in both Northern and Southern Vietnam. G6P[11] and G10P[11], which are combined G- and P-types, were identified in 71.4% and 28.6% of BoRVA-positive samples, respectively. Phylogenetic tree analysis revealed that the G6-type detected in Vietnamese cows is similar to strains derived from China, Japan, and Korea, whereas the G10 type is closely related to the Chinese strain. In addition, the P11 strain detected in Vietnamese cows is similar to the Spanish and Chinese strains. The BoRVA-positive rate was higher in cows aged less than 2 months (3.2%, 3/94) than in those aged 2 months or more (1.6%, 8/488). In summary, we detected the presence of G6P11 and G10P11 BoVRAs on Vietnamese cow farms, and found that they were more predominant in young calves than in older cows.