Delayed hypersensitivity reaction to cosmetic filler following two COVID-19 vaccinations and infection

With ongoing COVID-19 vaccination schedules and the popularity of cosmetic fillers, it is important to examine and record associated adverse reactions to a more general audience of health care professionals. Case reports exist in subspecialty journals outlining reactions after SARS-CoV-2 infection a...

Full description

Saved in:
Bibliographic Details
Published in:Allergy, asthma, and clinical immunology asthma, and clinical immunology, 2023-04, Vol.19 (1), p.31-31, Article 31
Main Authors: Azzouz, Safaa, Lanoue, Derek, Champagne, Katéri, Genest, Genevieve
Format: Article
Language:English
Subjects:
Antibiotics
Biopsy
Case Report
Complications and side effects
Coronaviruses
Cosmetic filler
COVID vaccine
COVID-19 vaccines
Cytokines
Delayed hypersensitivity reactions
Dermal fillers
Edema
Enzymes
Granulomas
Hyaluronic acid
Hyaluronic acid injection
Infection
Infections
Injections
Lupus
Medical personnel
Medical research
Medicine, Experimental
Patients
Proteins
RNA
Sarcoidosis
Severe acute respiratory syndrome coronavirus 2
Skin
Steroids
Tetracycline
Tetracyclines
Transplants & implants
Vaccination
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:With ongoing COVID-19 vaccination schedules and the popularity of cosmetic fillers, it is important to examine and record associated adverse reactions to a more general audience of health care professionals. Case reports exist in subspecialty journals outlining reactions after SARS-CoV-2 infection and vaccination. This is one of the first cases published in Canada, and it highlights priorities and challenges faced by physicians in assessing and managing patients presenting with adverse reactions post vaccination. We present a case of a 43 -year-old women with delayed type 4 hypersensitivity reaction to hyaluronic acid cosmetic filler triggered by COVID-19 mRNA vaccination. We outline the clinical presentation, diagnosis, complications, and treatment of a late inflammatory reaction to hyaluronic acid filler and highlight the treatment priorities for clinicians faced with similar presentations. The differential diagnosis of delayed onset nodules formation post filler injection is broad and includes redistribution of fillers, inflammatory reaction to biofilm, and delayed hypersensitivity reaction. As result, in order to make the right diagnosis, administer the appropriate treatment and achieve great cosmetic results, we highly recommend seeking expert opinion from dermatologist, plastic surgeon and allergist immunologist in a timely manner.
ISSN:1710-1484
1710-1492
1710-1492
DOI:10.1186/s13223-023-00788-1