Steroidal Saponins from the Genus Smilax and Their Biological Activities

The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversifie...

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Bibliographic Details
Published in:Natural products and bioprospecting 2017-08, Vol.7 (4), p.283-298
Main Authors: Tian, Li-Wen, Zhang, Zhen, Long, Hai-Lan, Zhang, Ying-Jun
Format: Article
Language:English
Subjects:
Biological activities
Biomedical and Life Sciences
Bioorganic Chemistry
Disorders
Food Science
Inflammatory diseases
Life Sciences
Medicinal Chemistry
Pharmacology/Toxicology
Plant Biochemistry
Plant Sciences
Review
Saponins
Smilax
Steroidal saponins
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Summary:The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types, including spirostane, isospirostane, furostane, pregnane, and cholestane. This review mainly summarizes the steroidal saponins ( 1 – 104 ) reported from the genus Smilax between 1967 and 2016, and their biological activities. The relationship between structures of steroidal saponins and related biological activities were briefly discussed. Graphical Abstract
ISSN:2192-2195
2192-2209
DOI:10.1007/s13659-017-0139-5