The relationship of preoperative estimated glomerular filtration rate and outcomes after cardiovascular surgery in patients with normal serum creatinine: a retrospective cohort study

Although serum creatinine concentration has been traditionally used as an index of renal function in clinical practice, it is considered relatively inaccurate, especially in patients with mild renal dysfunction. This study investigated the usefulness of preoperative estimated glomerular filtration r...

Full description

Saved in:
Bibliographic Details
Published in:BMC anesthesiology 2019-05, Vol.19 (1), p.88-88, Article 88
Main Authors: Jang, Myung-Soo, Nam, Jae-Sik, Jo, Jun-Young, Kang, Chang-Hwa, Ryu, Seung Ah, Lee, Eun-Ho, Choi, In-Cheol
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biomarkers - blood
Cardiovascular surgery
Cardiovascular Surgical Procedures - adverse effects
Cardiovascular Surgical Procedures - trends
Cardiovascular system
Clinical medicine
Cohort analysis
Cohort Studies
Collaboration
Complications
Coronary vessels
Creatinine
Creatinine - blood
Epidemiology
Epidermal growth factor receptors
Female
Glomerular filtration rate
Glomerular Filtration Rate - physiology
Glomerular filtration rate, creatinine
Health risks
Heart surgery
Humans
Kidney diseases
Kidneys
Male
Measurement
Medical records
Methods
Middle Aged
Mortality
Patient monitoring
Patients
Physiological aspects
Postoperative Complications - blood
Postoperative Complications - etiology
Preoperative Care - methods
Preoperative Care - trends
Renal function
Retrospective Studies
Sepsis
Studies
Surgery
Treatment Outcome
Variables
Wound infection
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although serum creatinine concentration has been traditionally used as an index of renal function in clinical practice, it is considered relatively inaccurate, especially in patients with mild renal dysfunction. This study investigated the usefulness of preoperative estimated glomerular filtration rate (eGFR) in predicting complications after cardiovascular surgery in patients with normal serum creatinine concentrations. This study included 2208 adults undergoing elective cardiovascular surgery. Preoperative eGFR was calculated using Chronic Kidney Disease Epidemiology Collaboration equations. The relationships between preoperative eGFR and 90 day postoperative composite major complications were analyzed, including 90 day all-cause mortality, major adverse cardiac and cerebrovascular events, severe acute kidney injury, respiratory and gastrointestinal complications, wound infection, sepsis, and multi-organ failure. Of the 2208 included patients, 185 (8.4%) had preoperative eGFR
ISSN:1471-2253
1471-2253
DOI:10.1186/s12871-019-0763-1