Trends of correlations between serum levels of growth hormone and insulin-like growth factor-I in general practice

Serum levels of growth hormone (GH) and insulin-like growth factor (IGF)-I are crucial in the diagnosis and management of GH-related diseases. However, these levels are affected by nutritional and metabolic status. To elucidate the correlations between GH and IGF-I in various conditions, a retrospec...

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Bibliographic Details
Published in:Frontiers in endocrinology (Lausanne) 2024-03, Vol.15, p.1381083-1381083
Main Authors: Oguni, Kohei, Yamamoto, Koichiro, Nakano, Yasuhiro, Soejima, Yoshiaki, Suyama, Atsuhito, Takase, Ryosuke, Yasuda, Miho, Hasegawa, Kou, Otsuka, Fumio
Format: Article
Language:English
Subjects:
acromegaly
Acromegaly - diagnosis
Adult
Albumins
Dwarfism, Pituitary
Endocrinology
General Practice
GH deficiency (GHD)
Growth Hormone
growth hormone (GH)
Human Growth Hormone
Humans
insulin-like growth factor (IGF)-I
Insulin-Like Growth Factor I - metabolism
Insulin-Like Peptides
pituitary gland
Retrospective Studies
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Summary:Serum levels of growth hormone (GH) and insulin-like growth factor (IGF)-I are crucial in the diagnosis and management of GH-related diseases. However, these levels are affected by nutritional and metabolic status. To elucidate the correlations between GH and IGF-I in various conditions, a retrospective analysis was performed for adult patients in which GH levels were examined by general practitioners during the period from January 2019 to December 2021. Of 642 patients, 33 patients were diagnosed with acromegaly, 21 were diagnosed with GH deficiency (GHD), and 588 were diagnosed with non-GH-related diseases (NGRD). In contrast to the positive correlations found between the levels of GH and IGF-I in patients with acromegaly ( =0.50;
ISSN:1664-2392
1664-2392
DOI:10.3389/fendo.2024.1381083