Magnetic nanoparticles in biomedical applications: A review

Biomedical applications with emphasis on the design of smart materials, specifically magnetic nanoparticles (MNPs) are considered to have technological benefits because they can be manipulated using magnetic fields. Magnetic NPs have been widely used in hyperthermia, target drug delivery system, ima...

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Bibliographic Details
Published in:Applied surface science advances 2021-12, Vol.6, p.100163, Article 100163
Main Authors: Materón, Elsa M., Miyazaki, Celina M., Carr, Olivia, Joshi, Nirav, Picciani, Paulo H.S., Dalmaschio, Cleocir J., Davis, Frank, Shimizu, Flavio M.
Format: Article
Language:English
Subjects:
Biomedical applications
Chronic diseases
Immunoassays
Magnetic nanoparticles
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Summary:Biomedical applications with emphasis on the design of smart materials, specifically magnetic nanoparticles (MNPs) are considered to have technological benefits because they can be manipulated using magnetic fields. Magnetic NPs have been widely used in hyperthermia, target drug delivery system, imaging, and extraction of biomolecules, postulating them also as an important tool in cancer treatment. Morphological structures of magnetic materials have drawn tremendous attention from diverse scientific fields due to their unique surface chemistry, nontoxicity, biocompatibility, and particularly their inducible magnetic moment. This review features recent research accomplishments made in the biomedical field using magnetic nanoparticles. The first part gives a comprehensive overview of magnetic nanoparticles in the treatment of chronic diseases and drug targeting. The second part includes the role of magnetic nanoparticles in electrochemical, optical-based immunoassays. The review also outlines the current challenges and future research perspectives for fostering advanced and high-performance magnetic nanoparticles in technological applications.
ISSN:2666-5239
2666-5239
DOI:10.1016/j.apsadv.2021.100163