Solvent free one pot synthesis of novel naphtho[1,8-gh] quinazoline-7,10-dione derivatives with CuCl2

The Biginelli-type reaction of phenalen-1,3-dione with urea, and benzaldehyde derivatives in the presence of CuCl2 as a catalyst for the synthesis of naphtho[1,8-gh]quinazoline-7,10-diones in solvent free condition are reviewed. Excellent yields of the products, short reaction times and simple work-...

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Bibliographic Details
Published in:Bulletin of the Chemical Society of Ethiopia 2018-01, Vol.32 (1), p.149-156
Main Author: K. Mohammadi, M.
Format: Article
Language:English
Subjects:
10-diones
8-gh]quinazoline-7
Naphtho
One pot
Solvent free
Synthesis
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Summary:The Biginelli-type reaction of phenalen-1,3-dione with urea, and benzaldehyde derivatives in the presence of CuCl2 as a catalyst for the synthesis of naphtho[1,8-gh]quinazoline-7,10-diones in solvent free condition are reviewed. Excellent yields of the products, short reaction times and simple work-up are attractive features of this suitable protocol.
ISSN:1011-3924
1726-801X
DOI:10.4314/bcse.v32i1.14