Low SARS-CoV-2 viral load among vaccinated individuals infected with Delta B.1.617.2 and Omicron BA.1.1.529 but not with Omicron BA.1.1 and BA.2 variants

The rapid spread of SARS-CoV-2 variants in the global population is indicative of the development of selective advantages in emerging virus strains. Here, we performed a case-control investigation of the clinical and demographic characteristics, clinical history, and virological markers to predict d...

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Published in:Frontiers in public health 2022-09, Vol.10, p.1018399-1018399
Main Authors: Selvavinayagam, Sivaprakasam T, Yong, Yean Kong, Joseph, Narcisse, Hemashree, Kannan, Tan, Hong Yien, Zhang, Ying, Rajeshkumar, Manivannan, Kumaresan, Anandhazhvar, Kalpana, Raghu, Kalaivani, Vasudevan, Monika, Ayyagari Venkata Devi, Suvaithenamudhan, Suvaiyarasan, Kannan, Meganathan, Murugesan, Amudhan, Narayanasamy, Krishnasamy, Palani, Sampath, Larsson, Marie, Shankar, Esaki M, Raju, Sivadoss
Format: Article
Language:English
Subjects:
AZD1222
BBV152
COVID-19 - epidemiology
COVID-19 severity
COVID-19 Testing
Disease Progression
Humans
India - epidemiology
Omicron BA.2
Phylogeny
Public Health
SARS-CoV-2 - genetics
Viral Load
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Summary:The rapid spread of SARS-CoV-2 variants in the global population is indicative of the development of selective advantages in emerging virus strains. Here, we performed a case-control investigation of the clinical and demographic characteristics, clinical history, and virological markers to predict disease progression in hospitalized adults for COVID-19 between December 2021 and January 2022 in Chennai, India. COVID-19 diagnosis was made by a commercial TaqPath COVID-19 RT-PCR, and WGS was performed with the Ion Torrent Next Generation Sequencing System. High-quality (
ISSN:2296-2565
2296-2565
DOI:10.3389/fpubh.2022.1018399