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Comparison between suction rectal biopsy and full-thickness rectal biopsy in the diagnosis of hirschsprung's disease
Aim: The aim of this study is to compare suction rectal biopsy (SRB) with full-thickness rectal biopsy (FTRB) in suspected cases of Hirschsprung's disease (HD). Materials and Methods: Between 2014 and 2018, we enrolled 41 consecutive children with suspected HD. We analyzed demographics, sex, ag...
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Published in: | Journal of Indian Association of Pediatric Surgeons 2021-07, Vol.26 (3), p.144-147 |
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description | Aim: The aim of this study is to compare suction rectal biopsy (SRB) with full-thickness rectal biopsy (FTRB) in suspected cases of Hirschsprung's disease (HD).
Materials and Methods: Between 2014 and 2018, we enrolled 41 consecutive children with suspected HD. We analyzed demographics, sex, age, clinical symptoms, radiological images, and biopsy reports. All the children had undergone X-ray of the abdomen and pelvis and contrast enema. All of them have undergone both SRB and FTRB, and their results were compared.
Results: Out of 41 children, 26 were male and 15 were female. The children were aged from 5 days to 12 years. All of them presented with delayed passage of meconium, abdominal distension, and severe constipation. They all were on oral laxatives. The sensitivity and specificity of SRB are 80.95% and 90.00% when compared to FTRB which has 100% and 100%, respectively.
Conclusion: FTRB is the gold standard test for diagnosing HD. SRB may be a good screening test in suspected HD cases. SRB is not as equal and effective as FTRB for diagnosing HD. |
doi_str_mv | 10.4103/jiaps.JIAPS_47_20 |
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Materials and Methods: Between 2014 and 2018, we enrolled 41 consecutive children with suspected HD. We analyzed demographics, sex, age, clinical symptoms, radiological images, and biopsy reports. All the children had undergone X-ray of the abdomen and pelvis and contrast enema. All of them have undergone both SRB and FTRB, and their results were compared.
Results: Out of 41 children, 26 were male and 15 were female. The children were aged from 5 days to 12 years. All of them presented with delayed passage of meconium, abdominal distension, and severe constipation. They all were on oral laxatives. The sensitivity and specificity of SRB are 80.95% and 90.00% when compared to FTRB which has 100% and 100%, respectively.
Conclusion: FTRB is the gold standard test for diagnosing HD. SRB may be a good screening test in suspected HD cases. SRB is not as equal and effective as FTRB for diagnosing HD.</description><identifier>ISSN: 0971-9261</identifier><identifier>EISSN: 1998-3891</identifier><identifier>DOI: 10.4103/jiaps.JIAPS_47_20</identifier><identifier>PMID: 34321784</identifier><language>eng</language><publisher>Kolkata: Wolters Kluwer India Pvt. Ltd</publisher><subject>Analysis ; Biopsy ; Birth defects ; Childrens health ; Diagnostic imaging ; full-thickness rectal biopsy ; hirschsprung's disease ; Original ; Rectum ; suction rectal biopsy</subject><ispartof>Journal of Indian Association of Pediatric Surgeons, 2021-07, Vol.26 (3), p.144-147</ispartof><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2021 Journal of Indian Association of Pediatric Surgeons 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c550s-69c12b51ea0db42682465cfa459dc1a3cf8fd97949e1fe941bd1b6e77a4797333</citedby><cites>FETCH-LOGICAL-c550s-69c12b51ea0db42682465cfa459dc1a3cf8fd97949e1fe941bd1b6e77a4797333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286026/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2535395374?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,25731,27901,27902,36989,36990,44566,53766,53768</link.rule.ids></links><search><creatorcontrib>Redkar, Rajeev</creatorcontrib><creatorcontrib>Chigicherla, Swathi</creatorcontrib><creatorcontrib>Tewari, Shruti</creatorcontrib><creatorcontrib>Sharma, Rahul</creatorcontrib><title>Comparison between suction rectal biopsy and full-thickness rectal biopsy in the diagnosis of hirschsprung's disease</title><title>Journal of Indian Association of Pediatric Surgeons</title><description>Aim: The aim of this study is to compare suction rectal biopsy (SRB) with full-thickness rectal biopsy (FTRB) in suspected cases of Hirschsprung's disease (HD).
Materials and Methods: Between 2014 and 2018, we enrolled 41 consecutive children with suspected HD. We analyzed demographics, sex, age, clinical symptoms, radiological images, and biopsy reports. All the children had undergone X-ray of the abdomen and pelvis and contrast enema. All of them have undergone both SRB and FTRB, and their results were compared.
Results: Out of 41 children, 26 were male and 15 were female. The children were aged from 5 days to 12 years. All of them presented with delayed passage of meconium, abdominal distension, and severe constipation. They all were on oral laxatives. The sensitivity and specificity of SRB are 80.95% and 90.00% when compared to FTRB which has 100% and 100%, respectively.
Conclusion: FTRB is the gold standard test for diagnosing HD. SRB may be a good screening test in suspected HD cases. SRB is not as equal and effective as FTRB for diagnosing HD.</description><subject>Analysis</subject><subject>Biopsy</subject><subject>Birth defects</subject><subject>Childrens health</subject><subject>Diagnostic imaging</subject><subject>full-thickness rectal biopsy</subject><subject>hirschsprung's disease</subject><subject>Original</subject><subject>Rectum</subject><subject>suction rectal biopsy</subject><issn>0971-9261</issn><issn>1998-3891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp1kk2P0zAQhiMEYpeFH8AtEge4pPgzji9IVcVH0UogAWfLdiap29QudrLV_nvc7fLRVZEPlmee953xaIriJUYzhhF9u3Z6l2afl_Ov3xQTiqBHxSWWsqloI_Hj4hJJgStJanxRPEtpjRBliOOnxQVllGDRsMtiXITtTkeXgi8NjHsAX6bJji6_I9hRD6VxYZduS-3bspuGoRpXzm48pPQAcL4cV1C2Tvc-JJfK0JUrF5NdpV2cfP865VwCneB58aTTQ4IX9_dV8ePD---LT9X1l4_Lxfy6spyjVNXSYmI4Bo1aw0jdEFZz22nGZWuxprZrulYKySTgDiTDpsWmBiE0E1JQSq-K5dG3DXqtdtFtdbxVQTt1FwixVzqOzg6gkOFNTRprhTVMYGNA5moCWcOztTDZ693RazeZLbQW_Bj1cGJ6mvFupfpwoxrS1IjU2eDNvUEMPydIo9q6ZGEYtIcwJUU4r2lG60Pfrx6g6zBFn0eVKcqp5FSwv1Sv8wec70Kuaw-mal7XRJCmIShT1RmqBw-5yeChczl8ws_O8Pm0sHX2rAAfBTaGlCJ0f2aCkTqsqbpbU_XPmmbN4qjZh2GEmDbDtIeo8vQ2Puz_L1SYMfV7Y-kv6mTz4g</recordid><startdate>20210701</startdate><enddate>20210701</enddate><creator>Redkar, Rajeev</creator><creator>Chigicherla, Swathi</creator><creator>Tewari, Shruti</creator><creator>Sharma, Rahul</creator><general>Wolters Kluwer India Pvt. 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Materials and Methods: Between 2014 and 2018, we enrolled 41 consecutive children with suspected HD. We analyzed demographics, sex, age, clinical symptoms, radiological images, and biopsy reports. All the children had undergone X-ray of the abdomen and pelvis and contrast enema. All of them have undergone both SRB and FTRB, and their results were compared.
Results: Out of 41 children, 26 were male and 15 were female. The children were aged from 5 days to 12 years. All of them presented with delayed passage of meconium, abdominal distension, and severe constipation. They all were on oral laxatives. The sensitivity and specificity of SRB are 80.95% and 90.00% when compared to FTRB which has 100% and 100%, respectively.
Conclusion: FTRB is the gold standard test for diagnosing HD. SRB may be a good screening test in suspected HD cases. SRB is not as equal and effective as FTRB for diagnosing HD.</abstract><cop>Kolkata</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>34321784</pmid><doi>10.4103/jiaps.JIAPS_47_20</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Analysis Biopsy Birth defects Childrens health Diagnostic imaging full-thickness rectal biopsy hirschsprung's disease Original Rectum suction rectal biopsy |
title | Comparison between suction rectal biopsy and full-thickness rectal biopsy in the diagnosis of hirschsprung's disease |
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