Effect of premedication on the success of inferior alveolar nerve block in patients diagnosed with irreversible pulpitis: An umbrella review

Successful management of pain during endodontic treatment is essential for both patients and dentists. Achieving adequate pulp anesthesia in mandibular molars is a significant concern for patients with irreversible pulpitis during endodontic treatment. The increased sensitization of nociceptors due...

Full description

Saved in:
Bibliographic Details
Published in:Dental research journal 2023, Vol.20 (1), p.75-75
Main Authors: Khademi, Abbasali, Iranmanesh, Pedram, Mosayebi, Neda, Heydari, Mahboobeh, Bagherieh, Shervin
Format: Article
Language:English
Subjects:
Alveoli
Anesthesia
Anesthetics
Drug delivery
Inflammation
mandibular nerve
Molars
Nociceptors
Pain perception
pulpitis
Review
Root canals
Success
systematic review
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Successful management of pain during endodontic treatment is essential for both patients and dentists. Achieving adequate pulp anesthesia in mandibular molars is a significant concern for patients with irreversible pulpitis during endodontic treatment. The increased sensitization of nociceptors due to inflammation decreases the success of inferior alveolar nerve block (IANB). The main focus is on reducing inflammation before delivery of local anesthesia to increase the success of anesthetic drugs. This umbrella review aimed to revise, qualify and summarize the existing body of evidence on the effect of premedication on IANB in patients with irreversible pulpitis. A literature search was conducted using electronic databases (PubMed, Scopus, the Web of Science, and the Cochrane Library) with no date restriction until September 2021 to identify the relevant studies. All the cross-references of the selected studies and grey literature were also screened. Four systematic reviews assessing the effect of premedication on the success of IANB were selected. A conclusion was drawn that premedication with >400 mg of ibuprofen can positively affect the success of IANB.
ISSN:1735-3327
2008-0255
DOI:10.4103/1735-3327.379632