Outer Retinal Layers’ Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes

Purpose. To identify and correlate age-related changes in outer retinal layers’ thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design. Observational cross-sectional study....

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Bibliographic Details
Published in:Journal of ophthalmology 2019, Vol.2019 (2019), p.1-8
Main Authors: Mohamed Ebeid, Weam, Abdelmonsef Abdelhamid Ebeid, Ahmed, Abdelmaguid Mohamed Elzankalony, Yasser, Kamal Abdellatif, Mona
Format: Article
Language:English
Subjects:
Age
Patients
Photoreceptors
Software
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Summary:Purpose. To identify and correlate age-related changes in outer retinal layers’ thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes. Study Design. Observational cross-sectional study. Subjects and Methods. We studied 125 healthy Egyptians between 20 and 79 years old. Patients were divided into 3 groups: group 1 (20–40 years), group 2 (40–60 years), and group 3 (>60 years). All patients had full ophthalmic examination. SD-OCT was done to measure the 9 ETDRS macular grid sectors of retinal pigment epithelium and photoreceptor outer segment (RPE-OS), outer nuclear layer and photoreceptor inner segment (ONL-IS), and choroidal thickness (CT) (by enhanced depth imaging). Results. RPE-OS was significantly thinner in group 3 than in the other 2 groups (central: P
ISSN:2090-004X
2090-0058
DOI:10.1155/2019/1698967