Infective endocarditis in Turkey: aetiology, clinical features, and analysis of risk factors for mortality in 325 cases

• Published in: International journal of infectious diseases 2015-01, Vol.30 (C), p.106-114
• Main Authors: Şimşek-Yavuz, Serap, Şensoy, Ayfer, Kaşıkçıoğlu, Hulya, Çeken, Sabahat, Deniz, Denef, Yavuz, Atilla, Koçak, Funda, Midilli, Kenan, Eren, Mehmet, Yekeler, İbrahim
• Format: Article
• Language: English
• Subjects: Adult; Aetiology; Aged; Endocarditis, Bacterial - diagnosis; Endocarditis, Bacterial - etiology; Endocarditis, Bacterial - microbiology; Endocarditis, Bacterial - mortality; Enterococcus - isolation & purification; Female; Gram-Positive Bacterial Infections - diagnosis; Gram-Positive Bacterial Infections - microbiology; Gram-Positive Bacterial Infections - mortality; Humans; Infectious Disease; Infective endocarditis; Male; Middle Aged; Mortality risk factors; Pulmonary/Respiratory; Risk Factors; Staphylococcal Infections - diagnosis; Staphylococcal Infections - microbiology; Staphylococcal Infections - mortality; Staphylococcus - isolation & purification; Streptococcal Infections - diagnosis; Streptococcal Infections - microbiology; Streptococcal Infections - mortality; Streptococcus - isolation & purification; Turkey - epidemiology
• ISSN: 1201-9712; 1878-3511
• DOI: 10.1016/j.ijid.2014.11.007

Highlights • Brucella spp should be considered as a frequent cause of infective endocarditis (IE) in Turkey. • Community-acquired native valve IE in younger patients is generally caused by streptococci. • Healthcare-associated and pacemaker lead IE are generally caused by staphylococci. • Late prosthetic valve IE with perivalvular abscess in older patients is generally caused by enterococci. • The prevention, early detection, and effective treatment of bacteraemia are very important in chronic haemodialysis patients because of the unacceptably high mortality rate of subsequent IE among these patients.