Safety and efficacy of fibrin glue versus infinity suture in SICS with extended scleral flap

Purpose: To study the safety and efficacy of biologic fibrin glue (FG) in comparison with infinity suture in SICS with compromised scleral flap. Methods: A retrospective comparative study of patients who were treated with FG (Group A) with 10-0 nylon (Group B) as sealing agent for intraoperative com...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2018-05, Vol.66 (5), p.657-660
Main Authors: Ambastha, Anita, Kusumesh, Rakhi, Bhasker, Gyan, Sinha, Bibhuti
Format: Article
Language:English
Subjects:
Adhesives
Anterior chamber
Care and treatment
Cataracts
Compromised tunnel
Ethical aspects
extended scleral flap
Eye surgery
Fibrin
fibrin glue
Gandhi, Indira (1917-84)
Infections
Management
Medical research
Medical supplies
Myopia
Ophthalmology
Original
Patients
Sealing compounds
small incision cataract surgery
Statistical analysis
surgically induced astigmatism
suture
Sutures
Tensile strength
Tunnels
Wounds
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Summary:Purpose: To study the safety and efficacy of biologic fibrin glue (FG) in comparison with infinity suture in SICS with compromised scleral flap. Methods: A retrospective comparative study of patients who were treated with FG (Group A) with 10-0 nylon (Group B) as sealing agent for intraoperative compromised tunnels in SICS. Parameters noted were postoperative inflammation, wound integrity, anterior chamber (AC) depth, intraocular pressure (IOP), and surgically induced astigmatism (SIA) at postoperative day 1, 4 weeks, 6 weeks, and 6 months, respectively. Epi Info 7 software and SIA calculator, Version 2.1 were used to analyze the result. Results: We reviewed the two groups of 18 patients each and noted that there was no statistically significant difference in postoperative inflammation (P > 0.05), AC depth (P > 0.05), and IOP (P > 0.05) between both groups at each postoperative visit. One patient in Group A showed postoperative shallow AC and subconjunctival bleb. Exposed sutures causing foreign body sensation had to be removed in five patients in Group B. At the end of 6-month postoperative period, no statistically significant difference was found in SIA (P = 0.92) between the two groups. Conclusion: Biologic FG can be safely used in securing the compromised scleral incisions in SICS. It also avoids suture-related complications.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_956_17