Graphene-based biosensors for disease theranostics: Development, applications, and recent advancements

Graphene, owing to its unique chemical structure and extraordinary chemical, electrical, thermal, optical, and mechanical properties, has opened up a new vista of applications, specifically as novel sensing platforms. The last decade has seen an extensive exploration of graphene and graphene-based m...

Full description

Saved in:
Bibliographic Details
Published in:Nanotechnology reviews (Berlin) 2022-01, Vol.11 (1), p.96-116
Main Authors: Alhazmi, Hassan A., Ahsan, Waquar, Mangla, Bharti, Javed, Shamama, Hassan, Mohd. Zaheen, Asmari, Mufarreh, Al Bratty, Mohammed, Najmi, Asim
Format: Article
Language:English
Subjects:
application
Biomarkers
Biomedical materials
Biosensors
Clinical trials
COVID-19
detection
Detection limits
Fabrication
functionalization
Graphene
Mechanical properties
Nanoparticles
Optical properties
Polymers
Precision medicine
SARS-CoV-2
Selectivity
Severe acute respiratory syndrome coronavirus 2
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Graphene, owing to its unique chemical structure and extraordinary chemical, electrical, thermal, optical, and mechanical properties, has opened up a new vista of applications, specifically as novel sensing platforms. The last decade has seen an extensive exploration of graphene and graphene-based materials either alone or modified with nanoparticles and polymers for the fabrication of nanoscale biosensors. These biosensors displayed excellent conductivity, high sensitivity, and selectivity, good accuracy, and precision, rapid detection with low detection limits as well as long-term stability. The unmatched properties of graphene and graphene-based materials have been applied for the detection of a number of chemical and biological molecules successfully for the diagnosis of a variety of diseases, pathogens, and biomarkers of the diseases. This review is aimed to cover the fabrication methods, functionalization techniques, and biomedical applications along with the recent advancements in the field of development of graphene-based biosensors. Recent clinical trials and patents as well as market trends and opportunities associated with graphene-based biosensors are also summarized. The application of graphene-based biosensors in the detection of SARS-CoV-2 causing COVID-19 is also reviewed.
ISSN:2191-9097
2191-9089
2191-9097
DOI:10.1515/ntrev-2022-0009