You Are What You Eat: Application of Metabolomics Approaches to Advance Nutrition Research

A healthy condition is defined by complex human metabolic pathways that only function properly when fully satisfied by nutritional inputs. Poor nutritional intakes are associated with a number of metabolic diseases, such as diabetes, obesity, atherosclerosis, hypertension, and osteoporosis. In recen...

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Published in:Foods 2021-05, Vol.10 (6), p.1249
Main Authors: Emwas, Abdul-Hamid M., Al-Rifai, Nahla, Szczepski, Kacper, Alsuhaymi, Shuruq, Rayyan, Saleh, Almahasheer, Hanan, Jaremko, Mariusz, Brennan, Lorraine, Lachowicz, Joanna Izabela
Format: Article
Language:English
Subjects:
Arteriosclerosis
Atherosclerosis
Biomedical materials
Chromatography
Complexity
COVID-19
Diabetes mellitus
Diet
Experiments
Food
Food products
Food science
Functional foods & nutraceuticals
Genomes
Hypertension
Metabolic disorders
Metabolic pathways
Metabolism
Metabolites
Metabolomics
NMR
Nuclear magnetic resonance
Nutrition
Nutrition research
Osteoporosis
Proteomics
Review
Toxicology
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creator Emwas, Abdul-Hamid M.
Al-Rifai, Nahla
Szczepski, Kacper
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Almahasheer, Hanan
Jaremko, Mariusz
Brennan, Lorraine
Lachowicz, Joanna Izabela
description A healthy condition is defined by complex human metabolic pathways that only function properly when fully satisfied by nutritional inputs. Poor nutritional intakes are associated with a number of metabolic diseases, such as diabetes, obesity, atherosclerosis, hypertension, and osteoporosis. In recent years, nutrition science has undergone an extraordinary transformation driven by the development of innovative software and analytical platforms. However, the complexity and variety of the chemical components present in different food types, and the diversity of interactions in the biochemical networks and biological systems, makes nutrition research a complicated field. Metabolomics science is an “-omic”, joining proteomics, transcriptomics, and genomics in affording a global understanding of biological systems. In this review, we present the main metabolomics approaches, and highlight the applications and the potential for metabolomics approaches in advancing nutritional food research.
doi_str_mv 10.3390/foods10061249
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subjects Arteriosclerosis
Atherosclerosis
Biomedical materials
Chromatography
Complexity
COVID-19
Diabetes mellitus
Diet
Experiments
Food
Food products
Food science
Functional foods & nutraceuticals
Genomes
Hypertension
Metabolic disorders
Metabolic pathways
Metabolism
Metabolites
Metabolomics
NMR
Nuclear magnetic resonance
Nutrition
Nutrition research
Osteoporosis
Proteomics
Review
Toxicology
title You Are What You Eat: Application of Metabolomics Approaches to Advance Nutrition Research
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