Bullous pemphigoid and neurological disease: statistics from a dermatology service

Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the production of autoantibodies against hemidesmosomes' components in the basement membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million inhabitants per year. Several studies have report...

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Bibliographic Details
Published in:Anais brasileiros de dermatología 2015-04, Vol.90 (2), p.280-282
Main Authors: Tarazona, Monica Jidid Mateus, Mota, Amanda Nascimento Cavalleiro de Macedo, Gripp, Alexandre Carlos, Unterstell, Natasha, Bressan, Aline Lopes
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Age Factors
Aged
Aged, 80 and over
Brazil - epidemiology
Communication
Dementia
DERMATOLOGY
Female
Humans
Male
Middle Aged
Nervous System Diseases - complications
Nervous System Diseases - epidemiology
Pemphigoid, bullous
Pemphigoid, Bullous - complications
Pemphigoid, Bullous - epidemiology
Prevalence
Retrospective Studies
Sex Distribution
Stroke
Stroke - complications
Stroke - epidemiology
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Summary:Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the production of autoantibodies against hemidesmosomes' components in the basement membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million inhabitants per year. Several studies have reported an association between BP and neurological disorders (ND). Our cohort of Bullous pemphigoid and ND is the first in Brazil and showed a significantly high prevalence of neurological and/or psychiatric diseases, especially cerebrovascular accident (CVA) and dementia, in agreement with the prevalence reported in several studies published in the medical literature in recent years.
ISSN:0365-0596
1806-4841
1806-4841
0365-0596
DOI:10.1590/abd1806-4841.20153334