The effect of intracanal cryotherapy with and without foraminal enlargement on pain prevention after endodontic treatment: a randomized clinical trial

This randomized clinical trial aims to evaluate cryotherapy as a therapeutic option for pain prevention after endodontic treatment with and without foraminal enlargement, in patients with asymptomatic apical periodontitis.120 teeth of patients with preoperative Visual Analogue Scale score indicating...

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Bibliographic Details
Published in:Scientific reports 2024-08, Vol.14 (1), p.19905-8
Main Authors: Iparraguirre Nuñovero, Marcos Felipe, Hungaro Duarte, Marco Antonio, Kaled Segato, André Vinícius, da Silva Neto, Ulisses Xavier, Portela Ditzel Westphalen, Vania, Carneiro, Everdan
Format: Article
Language:English
Subjects:
692/1807/410/2610
692/699/3017/3019
Adult
Clinical trials
Cryotherapy
Cryotherapy - methods
Enlargement
Female
Humanities and Social Sciences
Humans
Male
Middle Aged
multidisciplinary
Pain
Pain, Postoperative - etiology
Pain, Postoperative - prevention & control
Pain, Postoperative - therapy
Patients
Periapical Periodontitis - surgery
Periapical Periodontitis - therapy
Periodontitis
Prevention
Root Canal Preparation - methods
Root Canal Therapy - adverse effects
Root Canal Therapy - methods
Root canals
Science
Science (multidisciplinary)
Statistical analysis
Teeth
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Summary:This randomized clinical trial aims to evaluate cryotherapy as a therapeutic option for pain prevention after endodontic treatment with and without foraminal enlargement, in patients with asymptomatic apical periodontitis.120 teeth of patients with preoperative Visual Analogue Scale score indicating zero were treated. Specimens were randomly allocated into 4 groups: Control, Cryotherapy (ICT), Foraminal Enlargement (FE), and Cryotherapy and Foraminal Enlargement (ICT + FE). Working length was determined with an Electronic Apex Locator (EAL). Cryotherapy groups passed through a final irrigation protocol using 20 ml (2.5 ℃) of cold saline solution delivered at working length for 5 min. In FE groups a #40 K-file was used up to the 0.0 mark on the EAL display. Obturation was performed and postoperative pain was checked at 6, 12, 24, 48, and 72 h and 7 days after endodontic treatment.All experimental groups showed an increase in the level of postoperative pain, which started to decrease after 12 h. Foraminal enlargement caused a statistically significant increase in postoperativepain compared to ICT and control groups within the first 6 h (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-70901-w