Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice

Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Appro...

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Bibliographic Details
Published in:Frontiers in oncology 2021-05, Vol.11, p.630972-630972
Main Authors: Zhang, Yang, Zhang, Tao, Yang, Wenbo, Chen, Hongze, Geng, Xinglong, Li, Guanqun, Chen, Hua, Wang, Yongwei, Li, Le, Sun, Bei
Format: Article
Language:English
Subjects:
diet
ketogenic diet
low-sugar diet
Mediterranean diet
Oncology
pancreatic cancer
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Summary:Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Approximately 50% of PC cases are induced by an unhealthy diet, which can be avoided. Given this large attribution to diet, numerous studies have assessed the relationship between various dietary factors and PC. This article reviews three beneficial diets: a ketogenic diet (KD), a Mediterranean diet (MD), and a low-sugar diet. Their composition and impact mechanism are summarized and discussed. The associations between these three diets and PC were analyzed, and we aimed to provide more help and new insights for the prevention and treatment of PC.
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2021.630972