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Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging

Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalati...

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Bibliographic Details
Published in:Nanomaterials (Basel, Switzerland) Switzerland), 2023-03, Vol.13 (6), p.1102
Main Authors: Yu, Seungjin, Choi, Goeun, Choy, Jin-Ho
Format: Article
Language:English
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Summary:Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging.
ISSN:2079-4991
2079-4991
DOI:10.3390/nano13061102