Reconstruction of intraoral oncologic surgical defects with Integra® bilayer wound matrix

Utilization of biologic skin substitutes for the management of soft tissue defects as an alternative to autologous skin grafts has expanded over the past 2 decades. The purpose of this case series study was to report our experience with Integra® bilayer wound matrix for reconstruction of intraoral o...

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Bibliographic Details
Published in:Clinical case reports 2021-01, Vol.9 (1), p.213-219
Main Authors: Srivastava, Akanksha, Maniakas, Anastasios, Myers, Jeffrey, Chambers, Mark S., Cardoso, Richard
Format: Article
Language:English
Subjects:
biosynthetic skin substitutes
Cancer
Case Report
Case Reports
Defects
Morbidity
Mouth
Oral cancer
oral reconstruction
Patients
Plastic surgery
Polymethyl methacrylate
Prostheses
Skin & tissue grafts
Sutures
Tumors
wound healing
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Summary:Utilization of biologic skin substitutes for the management of soft tissue defects as an alternative to autologous skin grafts has expanded over the past 2 decades. The purpose of this case series study was to report our experience with Integra® bilayer wound matrix for reconstruction of intraoral oncologic defects. Case records of 6 patients with intraoral oncologic defects reconstructed with Integra® bilayer wound matrix were retrospectively reviewed. The surgical defect location, size, and time to removal of surgical splint varied. Clinically, normal oral epithelialization was noted for all patients. One patient demonstrated a small area of dehiscence and bone exposure after adjuvant radiation therapy which resolved with minimal intervention. Integra bilayer wound matrix is a viable and versatile option for reconstruction of intraoral oncologic surgical defects. Further exploration of wound healing with Integra® matrix, surgical techniques, and cost‐effectiveness is advocated. Integra® bilayer wound matrix is a viable and versatile option for reconstruction of small to large intraoral oncologic surgical defects on movable and nonmoveable mucosa.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.3501