Motor band sign or biomarker

• Published in: iRadiology (Online) 2023-12, Vol.1 (4), p.378-380
• Main Authors: Ghaderi, Sadegh, Mohammadi, Sana
• Format: Article
• Language: English
• Subjects: Amyotrophic lateral sclerosis; Biomarkers; Conflicts of interest; Disease; Magnetic resonance imaging; Medical imaging; Medical prognosis; motor band sign; motor neuron disease; Neurodegeneration; Neuroimaging
• ISSN: 2834-2879; 2834-2860; 2834-2879
• DOI: 10.1002/ird3.43

Abbreviations ALS amyotrophic lateral sclerosis LMN lower motor neuron MBS motor band sign MND motor neuron disease MRI magnetic resonance imaging QSM quantitative susceptibility mapping SWI susceptibility-weighted imaging UMN upper motor neuron Motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), are a group of devastating and progressive neurodegenerative disorders that affect the upper and lower motor neurons (UMN and LMN) []. Early and accurate diagnosis is critical; yet the diagnosis and prognosis of MNDs are challenging due to the complexity and heterogeneity of these diseases. [...]there is a need for sensitive, suggestive, and reliable biomarkers to detect and monitor the progression of neurodegeneration and neuroinflammation in MNDs []. Sadegh Ghaderi participated in the conception and design of the study; Sadegh Ghaderi and Sana Mohammadi constructively revised the manuscript; Sana Mohammadi participated in data collection and organization; Sadegh Ghaderi participated in and supervised the study throughout, and they share corresponding authorship.