Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?

Obesity is an increasingly widespread disease worldwide because of lifestyle changes. It is associated with an increased risk of cardiovascular disease, primarily type 2 diabetes mellitus, with an increase in major cardiovascular adverse events. Bariatric surgery has been shown to be able to reduce...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Switzerland), 2023-07, Vol.13 (7), p.1552
Main Authors: Bottino, Roberta, Carbone, Andreina, Formisano, Tiziana, D'Elia, Saverio, Orlandi, Massimiliano, Sperlongano, Simona, Molinari, Daniele, Castaldo, Pasquale, Palladino, Alberto, Barbareschi, Consiglia, Tolone, Salvatore, Docimo, Ludovico, Cimmino, Giovanni
Format: Article
Language:English
Subjects:
Analysis
bariatric surgery
Body fat
Body mass index
cardiovascular disease
Cardiovascular diseases
Care and treatment
Complications and side effects
Development and progression
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetics
Food
Gastrointestinal surgery
Health aspects
Health risks
Insulin resistance
Metabolic disorders
Mortality
Obesity
Patients
Physiological aspects
Prostheses
Review
Risk assessment
Risk factors
Stomach
Surgery
Type 2 diabetes
Weight control
Weight loss
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Summary:Obesity is an increasingly widespread disease worldwide because of lifestyle changes. It is associated with an increased risk of cardiovascular disease, primarily type 2 diabetes mellitus, with an increase in major cardiovascular adverse events. Bariatric surgery has been shown to be able to reduce the incidence of obesity-related cardiovascular disease and thus overall mortality. This result has been shown to be the result of hormonal and metabolic effects induced by post-surgical anatomical changes, with important effects on multiple hormonal and molecular axes that make this treatment more effective than conservative therapy in determining a marked improvement in the patient's cardiovascular risk profile. This review, therefore, aimed to examine the surgical techniques currently available and how these might be responsible not only for weight loss but also for metabolic improvement and cardiovascular benefits in patients undergoing such procedures.
ISSN:2075-1729
2075-1729
DOI:10.3390/life13071552