JLIN: a java based linkage disequilibrium plotter

A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly used to examine and compare markers across increasingly...

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Bibliographic Details
Published in:BMC bioinformatics 2006-02, Vol.7 (1), p.60-60, Article 60
Main Authors: Carter, Kim W, McCaskie, Pamela A, Palmer, Lyle J
Format: Article
Language:English
Subjects:
Algorithms
Chromosome Mapping - methods
Computer Graphics
Database Management Systems
Databases, Genetic
Linkage Disequilibrium - genetics
Polymorphism, Genetic
Polymorphism, Single Nucleotide - genetics
Programming Languages
Sequence Analysis, DNA - methods
Software
User-Computer Interface
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Summary:A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly used to examine and compare markers across increasingly large datasets. Visualisation techniques are becoming essential to analyse the ever-growing volume of data and results available with any given analysis. JLIN (Java LINkage disequilibrium plotter) is a software package designed for customisable, intuitive visualisation of Linkage Disequilibrium (LD) across all common computing platforms. Customisation allows the user to choose particular visualisations, statistical measures and measurement ranges. JLIN also allows the user to export images of the LD visualisation in several common document formats. JLIN allows the user to visually compare and contrast the results of a range of statistical measures on the input dataset(s). These measures include the commonly used D' and r2 statistics and empirical p-values. JLIN has a number of unique and novel features that improve on existing LD visualisation tools.
ISSN:1471-2105
1471-2105
DOI:10.1186/1471-2105-7-60