Safety of photodynamic therapy involving optic nerve head

We present a case of large peripapillary polypoidal choroidal vasculopathy treated with standard-fluence photodynamic therapy (PDT) as other treatment options were unsuccessful or not justified. Due to large lesion size, treatment spot included part of optic disc also. PDT resulted in regression of...

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Published in:Indian journal of ophthalmology 2020-03, Vol.68 (3), p.530-533
Main Authors: Manayath, George, Verghese, Shishir, Jain, Nidhee, Ranjan, Ratnesh, Narendran, Venkatapathy
Format: Article
Language:English
Subjects:
Aflibercept
Case Reports
Choroid - blood supply
Civilian casualties
Female
Fluorescein Angiography - methods
Fundus Oculi
Humans
Lasers
Medical imaging
Middle Aged
Optic Disk - diagnostic imaging
Optic nerve
optic nerve head
Patients
Photochemotherapy
Photochemotherapy - methods
Photodynamic therapy
Photosensitizing Agents - therapeutic use
polypoidal choroidal vasculopathy
Polyps - diagnosis
Polyps - drug therapy
Ranibizumab
Tomography, Optical Coherence
Vascular diseases
Verteporfin
Verteporfin - therapeutic use
Visual Acuity
Visual evoked potentials
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container_issue 3
container_start_page 530
container_title Indian journal of ophthalmology
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creator Manayath, George
Verghese, Shishir
Jain, Nidhee
Ranjan, Ratnesh
Narendran, Venkatapathy
description We present a case of large peripapillary polypoidal choroidal vasculopathy treated with standard-fluence photodynamic therapy (PDT) as other treatment options were unsuccessful or not justified. Due to large lesion size, treatment spot included part of optic disc also. PDT resulted in regression of polyp and visual improvement (from 20/300 to 20/20) without any collateral damage to optic nerve as evidenced by visual-field test and visual-evoked potential with a follow-up till 2 years. This case highlights the role of PDT as a safe alternative for treatment of large peripapillary lesion, even though the treatment spot encompasses part of the optic nerve head.
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subjects Aflibercept
Case Reports
Choroid - blood supply
Civilian casualties
Female
Fluorescein Angiography - methods
Fundus Oculi
Humans
Lasers
Medical imaging
Middle Aged
Optic Disk - diagnostic imaging
Optic nerve
optic nerve head
Patients
Photochemotherapy
Photochemotherapy - methods
Photodynamic therapy
Photosensitizing Agents - therapeutic use
polypoidal choroidal vasculopathy
Polyps - diagnosis
Polyps - drug therapy
Ranibizumab
Tomography, Optical Coherence
Vascular diseases
Verteporfin
Verteporfin - therapeutic use
Visual Acuity
Visual evoked potentials
title Safety of photodynamic therapy involving optic nerve head
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