Cardiomyopathy and Sudden Cardiac Death: Bridging Clinical Practice with Cutting-Edge Research

Sudden cardiac death (SCD) prevention in cardiomyopathies such as hypertrophic (HCM), dilated (DCM), non-dilated left ventricular (NDLCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC) remains a crucial but complex clinical challenge, especially among younger populations. Accurate risk...

Full description

Saved in:
Bibliographic Details
Published in:Biomedicines 2024-07, Vol.12 (7), p.1602
Main Authors: Mistrulli, Raffaella, Ferrera, Armando, Salerno, Luigi, Vannini, Federico, Guida, Leonardo, Corradetti, Sara, Addeo, Lucio, Valcher, Stefano, Di Gioia, Giuseppe, Spera, Francesco Raffaele, Tocci, Giuliano, Barbato, Emanuele
Format: Article
Language:English
Subjects:
Age
Cardiac arrhythmia
Cardiology
cardiomyopathies
Cardiomyopathy
cardiovascular prevention
Clinical medicine
Genetic variability
Heart
Lifesaving
Magnetic resonance imaging
Medical prognosis
Patients
Population genetics
Prevention
Risk factors
risk stratification
sudden cardiac death
Ventricle
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sudden cardiac death (SCD) prevention in cardiomyopathies such as hypertrophic (HCM), dilated (DCM), non-dilated left ventricular (NDLCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC) remains a crucial but complex clinical challenge, especially among younger populations. Accurate risk stratification is hampered by the variability in phenotypic expression and genetic heterogeneity inherent in these conditions. This article explores the multifaceted strategies for preventing SCD across a spectrum of cardiomyopathies and emphasizes the integration of clinical evaluations, genetic insights, and advanced imaging techniques such as cardiac magnetic resonance (CMR) in assessing SCD risks. Advanced imaging, particularly CMR, not only enhances our understanding of myocardial architecture but also serves as a cornerstone for identifying at-risk patients. The integration of new research findings with current practices is essential for advancing patient care and improving survival rates among those at the highest risk of SCD. This review calls for ongoing research to refine risk stratification models and enhance the predictive accuracy of both clinical and imaging techniques in the management of cardiomyopathies.
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines12071602