Sensitivity of Awaji Criteria and Revised El Escorial Criteria in the Diagnosis of Amyotrophic Lateral Sclerosis (ALS) at First Visit in a Tunisian Cohort

Background. Amyotrophic lateral sclerosis (ALS) is a fatal disease whose diagnosis and early management can improve survival. The most used diagnostic criteria are the revised El Escorial criteria (rEEC) and Awaji criteria (AC). The comparison of their sensitivities showed contradictory results. Our...

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Bibliographic Details
Published in:Neurology research international 2021, Vol.2021, p.8841281-6
Main Authors: Ido, Bademain Jean Fabrice, Kacem, Imen, Ouedraogo, Mahamadi, Nasri, Amina, Mrabet, Saloua, Gargouri, Amina, Ben Djebara, Mouna, Kabore, Bawindsongré Jean, Gouider, Riadh
Format: Article
Language:English
Subjects:
Amyotrophic lateral sclerosis
Development and progression
Health aspects
Medical records
Medical research
Medicine, Experimental
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Summary:Background. Amyotrophic lateral sclerosis (ALS) is a fatal disease whose diagnosis and early management can improve survival. The most used diagnostic criteria are the revised El Escorial criteria (rEEC) and Awaji criteria (AC). The comparison of their sensitivities showed contradictory results. Our study aimed to compare the sensitivities of these two criteria in the diagnosis of definite ALS, at first visit, in a Tunisian hospital cohort. Materials and Methods. This was a retrospective study including 173 patients diagnosed with ALS at the Department of Neurology of the Razi Hospital between January 2003 and April 2018.After studying the clinical features of the disease in our study population,each patient was categorized according to the rEEC and AC based on data collected in his medical record during his first visit to our department. Then, we compared the sensitivities of these two criteria in the diagnosis of definite ALS. Results. Our Tunisian cohort was characterized by a slower disease progression. The sensitivity of the AC (69.4%) was significantly higher than that of the rEEC (40.5%) (p 
ISSN:2090-1852
2090-1860
DOI:10.1155/2021/8841281