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Immunological Follow-up of Hydatid Cyst Cases
Hydatid disease is caused by Echinococcus granulosus. In this study, we aimed to investigate the benefit of monitoring cases with hydatid cyst by means of immune components in patients in a long-term follow-up after surgery. Eighty-four preoperative and postoperative serum samples from 14 cases unde...
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Published in: | Memórias do Instituto Oswaldo Cruz 2001-07, Vol.96 (5), p.669-671 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Hydatid disease is caused by Echinococcus granulosus. In this study, we
aimed to investigate the benefit of monitoring cases with hydatid cyst
by means of immune components in patients in a long-term follow-up
after surgery. Eighty-four preoperative and postoperative serum samples
from 14 cases undergoing surgery for hydatid disease were evaluated in
terms of immune parameters, such as total and specific IgE, IgG, IgM,
IgA and complement. Total and specific IgE were determined by ELISA.
Specific IgG levels were measured by indirect hemaglutination.Total
IgG, IgM, IgA and complement (C3 and C4) were detected by nephelometry.
Imaging studies were also carried out during the follow-up. In none of
the patients hydatid cysts were detected during the follow-up. Total
IgE levels in the sera of the patients decreased to normal six months
after surgery. Although specific IgE against echinococcal antigens
decreased one year after operation, levels were still significantly
high. There were no changes in the levels of anti-Echinococcus IgG and
total IgG in follow-up period. Additionally, other parameters, such as
IgA, IgM, C3 and C4, were not affected. |
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ISSN: | 1678-8060 0074-0276 0074-0276 1678-8060 |
DOI: | 10.1590/S0074-02762001000500015 |