Stress-induced cardiomyopathy (Takotsubo)--broken heart and mind?

Stress-induced cardiomyopathy (SIC), also known as Takotsubo cardiomyopathy, is characterized by severe but potentially reversible regional left ventricular wall motion abnormalities, ie, akinesia, in the absence of explanatory angiographic evidence of a coronary occlusion. The typical pattern is th...

Full description

Saved in:
Bibliographic Details
Published in:Vascular health and risk management 2013-01, Vol.9 (default), p.149-154
Main Authors: Redfors, Björn, Shao, Yangzhen, Omerovic, Elmir
Format: Article
Language:English
Subjects:
Angiography
Brain
Brain - metabolism
Brain - physiopathology
Cardiac and Cardiovascular Systems
Cardiomyopathy
catecholamine
Catecholamines
Catecholamines - metabolism
cerebral injury
complications
Diagnosis
emotional stress
Emotions
etiology
Heart diseases
Heart Ventricles
Heart Ventricles - metabolism
Heart Ventricles - physiopathology
Humans
Kardiologi
Left
metabolism
Physiological aspects
physiopathology
Prognosis
Psychological
psychology
Review
Risk factors
somatic stress
Stress
Stress, Psychological - complications
Stress, Psychological - metabolism
Stress, Psychological - physiopathology
stress-induced cardiomyopathy
Takotsubo Cardiomyopathy
Takotsubo Cardiomyopathy - diagnosis
Takotsubo Cardiomyopathy - etiology
Takotsubo Cardiomyopathy - metabolism
Takotsubo Cardiomyopathy - physiopathology
Takotsubo Cardiomyopathy - psychology
Takotsubo Cardiomyopathy - therapy
therapy
Ventricular Function
Ventricular Function, Left
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Stress-induced cardiomyopathy (SIC), also known as Takotsubo cardiomyopathy, is characterized by severe but potentially reversible regional left ventricular wall motion abnormalities, ie, akinesia, in the absence of explanatory angiographic evidence of a coronary occlusion. The typical pattern is that of an akinetic apex with preserved contractions in the base, but other variants are also common, including basal or midmyocardial akinesia with preserved apical function. The pathophysiology of SIC remains largely unknown but catecholamines are believed to play a pivotal role. The diverse array of triggering events that have been linked to SIC are arbitrarily categorized as either emotional or somatic stressors. These categories can be considered as different elements of a continuous spectrum, linked through the interface of neurology and psychiatry. This paper reviews our current knowledge of SIC, with focus on the intimate relationship between the brain and the heart.
ISSN:1178-2048
1176-6344
1178-2048
DOI:10.2147/vhrm.s40163