Childhood sexual abuse predicts treatment outcome in conversion disorder/functional neurological disorder. An observational longitudinal study

Objective Explore trauma, stress, and other predictive factors for treatment outcome in conversion disorder/functional neurological disorder (CD/FND). Methods Prospective observational design. Clinical cohort study among consecutive outpatients with DSM‐IV CD/FND in a specialized mental health insti...

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Bibliographic Details
Published in:Brain and behavior 2020-03, Vol.10 (3), p.e01558-n/a
Main Authors: Van der Feltz‐Cornelis, Christina M., Allen, Sarah F., Van Eck van der Sluijs, Jonna F.
Format: Article
Language:English
Subjects:
Adult
Adult Survivors of Child Abuse - psychology
Adverse childhood experiences
Anxiety Disorders - psychology
Anxiety Disorders - therapy
Child sexual abuse
Childhood
childhood sexual abuse
Classification
Clinical outcomes
Comorbidity
Conversion disorder
Conversion Disorder - psychology
Conversion Disorder - therapy
Diagnostic and Statistical Manual of Mental Disorders
Female
functional neurological disorder
Humans
Longitudinal Studies
Male
Mental disorders
Mental health
Middle Aged
Neurological disorders
Original Research
Pathogenesis
Patients
predictive factors
Prognosis
Prospective Studies
Sex crimes
Sex Offenses - psychology
Stress
Studies
Surveys and Questionnaires
Trauma
Treatment Outcome
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Summary:Objective Explore trauma, stress, and other predictive factors for treatment outcome in conversion disorder/functional neurological disorder (CD/FND). Methods Prospective observational design. Clinical cohort study among consecutive outpatients with DSM‐IV CD/FND in a specialized mental health institution for somatic symptom disorders and related disorders (SSRD), presented between 1 February 2010 and 31 December 2017. Patient files were assessed for early childhood trauma, childhood sexual abuse, current stress, and other predictive factors. Patient‐related routine outcome monitoring (PROM) data were evaluated for treatment outcome at physical (Patient Health Questionnaire [PHQ15], Physical Symptoms Questionnaire [PSQ]) level as primary outcome, and depression (Patient Health Questionnaire [PHQ9]), anxiety (General Anxiety Disorder [GAD7]), general functioning (Short Form 36 Health Survey [SF36]), and pain (Brief Pain Inventory [BPI]) as secondary outcome. Results A total of 64 outpatients were included in the study. 70.3% of the sample reported childhood trauma and 64.1% a recent life event. Mean scores of patients proceeding to treatment improved. Sexual abuse in childhood (F(1, 28) = 30.068, β = 0.608 p 
ISSN:2162-3279
2162-3279
DOI:10.1002/brb3.1558