Cardiovascular Diseases in COPD: From Diagnosis and Prevalence to Therapy

Chronic obstructive pulmonary disease (COPD) is considered one of the leading causes of mortality. Cardiovascular comorbidities are diagnosed often in COPD patients, not only because of the common risk factors these two diseases share, but also because of the systemic inflammation which characterize...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Switzerland), 2023-05, Vol.13 (6), p.1299
Main Authors: Papaporfyriou, Anastasia, Bartziokas, Konstantinos, Gompelmann, Daniela, Idzko, Marco, Fouka, Evangelia, Zaneli, Stavrina, Bakakos, Petros, Loukides, Stelios, Papaioannou, Andriana I
Format: Article
Language:English
Subjects:
Airway management
Cardiac arrhythmia
Cardiac patients
cardiovascular comorbidities
Cardiovascular disease
Cardiovascular diseases
Cardiovascular system
Care and treatment
Chronic obstructive pulmonary disease
Comorbidity
Complications and side effects
COPD
COPD exacerbation
COPD treatment
Coronary vessels
Development and progression
Diagnosis
Drug therapy
Dyspnea
Epidemiology
Greece
Health aspects
Health services
Heart attacks
Heart failure
Hospitalization
Hospitals
Hypertension
Inflammation
Lung diseases
Lung diseases, Obstructive
Medical prognosis
Morbidity
Mortality
Obstructive lung disease
Pulmonary arteries
Quality of life
Respiratory agents
Review
Risk factors
Vein & artery diseases
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Summary:Chronic obstructive pulmonary disease (COPD) is considered one of the leading causes of mortality. Cardiovascular comorbidities are diagnosed often in COPD patients, not only because of the common risk factors these two diseases share, but also because of the systemic inflammation which characterizes COPD and has deleterious effects in the cardiovascular system. The comorbid cardiovascular diseases in COPD result in several difficulties in the holistic treatment of these patients and affect outcomes such as morbidity and mortality. Several studies have reported that mortality from cardiovascular causes is common among COPD patients, while the risk for acute cardiovascular events increases during COPD exacerbations and remains high for a long time even after recovery. In this review, we focus on the prevalence of cardiovascular comorbidities in COPD patients, presenting the evidence regarding the interaction of the pathophysiological pathways which characterize each disease. Furthermore, we summarize information regarding the effects of cardiovascular treatment on COPD outcomes and vice versa. Finally, we present the current evidence regarding the impact of cardiovascular comorbidities on exacerbations, quality of life and survival of COPD patients.
ISSN:2075-1729
2075-1729
DOI:10.3390/life13061299