Ascites in the Course of Plasma Cell Myeloma Complicated by AL Amyloidosis

A 60-year-old Caucasian male with plasma cell myeloma (PCM) immunoglobulin G (IgG) kappa, International Staging System stage 3, diagnosed 5 months ago, was admitted to the department of hematology due to progression of the disease. He had completed three cycles of chemotherapy comprising bortezomib,...

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Bibliographic Details
Published in:Turkish journal of haematology 2018-03, Vol.35 (1), p.71-72
Main Authors: Debski, Jakub, Usnarska-Zubkiewicz, Lidia, Kapelko-Słowik, Katarzyna, Pawluś, Aleksander, Zaleska-Dorobisz, Urszula, Kuliczkowski, Kazimierz
Format: Article
Language:English
Subjects:
Abdomen
amyloidosis
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
ascites
Ascites - pathology
Biopsy
Bone marrow
Chemotherapy
Disease Progression
Fatal Outcome
Hematology
Humans
Hypertension
Images in Hematology
Immunoglobulin Light-chain Amyloidosis - diagnosis
Immunoglobulin Light-chain Amyloidosis - etiology
Immunoglobulin Light-chain Amyloidosis - therapy
Laboratories
Male
Medical prognosis
Middle Aged
Multiple myeloma
Multiple Myeloma - complications
Multiple Myeloma - diagnosis
Multiple Myeloma - therapy
myeloma
Tıp
Tomography, X-Ray Computed
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Description
Summary:A 60-year-old Caucasian male with plasma cell myeloma (PCM) immunoglobulin G (IgG) kappa, International Staging System stage 3, diagnosed 5 months ago, was admitted to the department of hematology due to progression of the disease. He had completed three cycles of chemotherapy comprising bortezomib, thalidomide, and dexamethasone; one cycle comprising vincristine, doxorubicin, and dexamethasone; and two cycles comprising lenalidomide and dexamethasone, without any clinically significant response. Three weeks before visiting the hospital, the patient also started complaining of progressive weakness, impaired respiratory function, and abdominal distension; an abdominal ultrasound at the time revealed hepatosplenomegaly with ascites, most likely associated with portal hypertension and protein disturbance, which initially he tolerated very well.
ISSN:1300-7777
1308-5263
DOI:10.4274/tjh.2016.0262