Streptococcus pneumoniae serotype 19A in hospitalized children with invasive pneumococcal disease after the introduction of conjugated vaccines in Lima, Peru

The Pneumococcal conjugate vaccine (PCV) has decreased cases of invasive pneumococcal disease (IPD) worldwide. However, the impact of PCVs introduction may be affected by the serotype distribution in a specific context. Cross-sectional multicenter passive surveillance study of IPD cases in pediatric...

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Bibliographic Details
Published in:Journal of infection and public health 2024-01, Vol.17 (1), p.44-50
Main Authors: Ochoa, Theresa J, Del Águila, Olguita, Reyes, Isabel, Chaparro, Eduardo, Castillo, María E, Campos, Francisco, Saenz, Andrés, Hernandez, Roger, Luna-Muschi, Alessandra, Castillo-Tokumori, Franco, Montero, Andrea E, Gonzales, Brayan E, Mercado, Erik H
Format: Article
Language:English
Subjects:
Antimicrobial resistance
Children
Pneumococcal vaccine
Serotype
Streptococcus pneumoniae
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Summary:The Pneumococcal conjugate vaccine (PCV) has decreased cases of invasive pneumococcal disease (IPD) worldwide. However, the impact of PCVs introduction may be affected by the serotype distribution in a specific context. Cross-sectional multicenter passive surveillance study of IPD cases in pediatric patients hospitalized in Lima, Peru between 2016 and 2019 (after PCV13 introduction) to determine the serotype distribution and antimicrobial resistance of Streptococcus pneumoniae. Serotyping was performed by a sequential multiplex PCR and confirmed by whole genome sequencing. Eighty-five S. pneumoniae isolates were recovered (4.07/100,000 among children
ISSN:1876-0341
1876-035X
DOI:10.1016/j.jiph.2023.10.047