Focal Muscle Vibration (fMV) for Post-Stroke Motor Recovery: Multisite Neuroplasticity Induction, Timing of Intervention, Clinical Approaches, and Prospects from a Narrative Review

Despite newly available therapies for acute stroke and innovative prevention strategies, stroke remains the third leading cause of disability-adjusted life-years (DALYs) lost worldwide, mostly because more than half of stroke survivors aged 65 and over exhibit an incomplete functional recovery of th...

Full description

Saved in:
Bibliographic Details
Published in:Vibration 2023-08, Vol.6 (3), p.645-658
Main Authors: Viganò, Alessandro, Celletti, Claudia, Giuliani, Giada, Jannini, Tommaso B, Marenco, Francesco, Maestrini, Ilaria, Zumpano, Rosaceleste, Vicenzini, Edoardo, Altieri, Marta, Camerota, Filippo, Di Piero, Vittorio, Toscano, Massimiliano
Format: Article
Language:English
Subjects:
adaptive plasticity
Aged patients
Brain
Brain research
Brain stimulation
Care and treatment
focal muscle vibration (fMV)
Health aspects
Hyperactivity
Kinematics
Methods
Modulators
Narratives
Neural networks
neuroplasticity
non-invasive brain stimulation (NIBS)
Patients
Recovery
Recruitment
Rehabilitation
repetitive muscle vibration (rMV)
Spasticity
Spinal cord
Stroke
Stroke (Disease)
Symmetry
Vibration
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Despite newly available therapies for acute stroke and innovative prevention strategies, stroke remains the third leading cause of disability-adjusted life-years (DALYs) lost worldwide, mostly because more than half of stroke survivors aged 65 and over exhibit an incomplete functional recovery of the paretic limb. Given that a repeated sensory input is one of the most effective modulators of cortical motor and somatosensory structures, focal muscle vibration (fMV) is gaining growing interest as a safe, well-tolerated, and non-invasive brain stimulation technique to promote motor recovery after stroke with a long-lasting and clinically relevant improvement in strength, step symmetry, gait, and kinematics parameters. In this narrative review, we first summarize the structural (neural plasticity) and functional changes (network relearning) triggered by the stroke lesion and carried out at a brain and spinal cord level in an attempt to recover from the loss of function. Then, we will focus on the fMV’s plasticity-based mechanisms reporting evidence of a possible concurrently acting multisite plasticity induced by fMV. Finally, to understand what the most effective fMV rehabilitation protocol could be, we will report the most recent evidence regarding the different clinical approaches and timing of the fMV treatment, the related open issues, and prospects.
ISSN:2571-631X
2571-631X
DOI:10.3390/vibration6030040