Spleen stiffness can be employed to assess the efficacy of spontaneous portosystemic shunts in relieving portal hypertension

Spleen stiffness (SS) has been found to mirror dynamic changes in portal pressure after transjugular intrahepatic portosystemic shunt (TIPS) placement. However, there is no data available regarding SS in patients with spontaneous portosystemic shunting (SPSS), especially in regards to prediction of...

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Bibliographic Details
Published in:Annals of hepatology 2020-11, Vol.19 (6), p.691-693
Main Authors: Giuffrè, Mauro, Bedogni, Giorgio, Abazia, Cristiana, Masutti, Flora, Tiribelli, Claudio, Crocè, Lory Saveria
Format: Article
Language:English
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Summary:Spleen stiffness (SS) has been found to mirror dynamic changes in portal pressure after transjugular intrahepatic portosystemic shunt (TIPS) placement. However, there is no data available regarding SS in patients with spontaneous portosystemic shunting (SPSS), especially in regards to prediction of hepatic decompensation. We retrospectively selected patients with confirmed SPSS and esophageal varices (EVs) at endoscopic examination, and recorded any decompensating event (i.e., variceal hemorrhage, overt hepatic encephalopathy, refractory ascites, spontaneous bacterial peritonitis, hepatorenal syndrome) in the first twelve months following liver and spleen elastography. The patients who presented decompensating events showed lower platelet count (94.5 vs. 121.5 g/L, p 
ISSN:1665-2681
2659-5982
DOI:10.1016/j.aohep.2020.07.004