Computed tomography findings in patients with pulmonary tuberculosis and diabetes at an infectious disease hospital in China: a retrospective cross-sectional study

• Published in: BMC infectious diseases 2023-06, Vol.23 (1), p.436-436, Article 436
• Main Authors: Yang, Qianwen, Zhang, Rongping, Gao, Yan, Zhou, Chaoxin, Kong, Weifang, Tao, Wang, Zhang, Guojin, Shang, Lan
• Format: Article
• Language: English
• Subjects: Analysis; Bronchiectasis; Care and treatment; Chest; China; Classification; Communicable Diseases; Comorbidity; Computed tomography; Cross-Sectional Studies; CT imaging; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - diagnostic imaging; Diagnosis; Drug resistance; Exudation; Glucose; Hospitals; Humans; Infectious disease; Infectious diseases; Lesions; Low income groups; Lung diseases; Lungs; Lymphatic system; Medical imaging; Medical research; Medicine, Experimental; Patients; Pulmonary tuberculosis; Retrospective Studies; Tomography; Tomography, X-Ray Computed - methods; Tuberculosis; Tuberculosis, Pulmonary - complications; Tuberculosis, Pulmonary - diagnostic imaging; Tuberculosis, Pulmonary - epidemiology; Type 2 diabetes; Type 2 diabetes mellitus
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-023-08386-7

This study aimed to investigate the relationship between active pulmonary tuberculosis (TB) and type 2 diabetes mellitus (T2DM) by analysing the clinical features and computed tomography (CT) findings of patients with active pulmonary TB and comorbid T2DM (TB-DM) in the LiangShan Yi regions. We collected data from 154 hospitalised patients with TB-DM initially confirmed at an infectious disease hospital in the Liangshan Yi Autonomous Prefecture between 1 and 2019, and 31 December 2021. These were matched by sex and age ± 3 years to 145 hospitalised patients with initially confirmed pulmonary TB without comorbid T2DM (TB-NDM) over the same period. The clinical characteristics of the two groups were analysed separately. Three group-blinded radiologists independently analysed the CT findings and classified them into mild-to-moderate and severe groups. Severe chest CT lesion refers to a lesion that is less diffused or moderately dense and either exceeds the total volume of one lung, a high-density fused lesion greater than one-third of the volume of one lung, or a cavitary lesion with a maximum diameter ≥ 4 cm. No significant differences were observed in the presentation of clinical features. Regarding the severity of chest CT manifestation, patients with TB-DM had significantly more severe TB than those with TB-NDM (89.61% vs. 68.97%, P