Clinical and radiological features associated with rupture of pulmonary artery pseudoaneurysm: a retrospective study

• Published in: BMC pulmonary medicine 2024-08, Vol.24 (1), p.417-9, Article 417
• Main Authors: Liu, Min, Liu, Jixiang, Yu, Wei, Gao, Xiaoyan, Chen, Shi, Qin, Wei, Zhu, Ziyang, Li, Chenghong, Li, Fajiu, Zhai, Zhenguo
• Format: Article
• Language: English
• Subjects: Abdomen; Adult; Aged; Aneurysm, False - diagnostic imaging; Aneurysm, Ruptured - complications; Aneurysm, Ruptured - diagnostic imaging; Cardiovascular system; Care and treatment; Catheters; Cavitation; Comparative analysis; Complications and side effects; Embolization; Etiology; Female; Hemodynamics; Hemoptysis; Hemoptysis - etiology; Humans; Infections; Lung cancer; Male; Medical imaging; Middle Aged; Patients; Pseudoaneurysm; Pulmonary arteries; Pulmonary artery; Pulmonary Artery - diagnostic imaging; Pulmonary artery pseudoaneurysm; Pulmonary cavitation; Retrospective Studies; Risk Factors; Rupture; Success; Tomography; Tomography, X-Ray Computed; Tumors; Veins & arteries
• ISSN: 1471-2466; 1471-2466
• DOI: 10.1186/s12890-024-03225-0

Hemoptysis resulting from rupture of the pulmonary artery pseudoaneurysm (PAP) is massive and fatal, while factor contributing to the rupture of pseudoaneurysm remains elusive. This study aimed to elucidate the clinical and radiological features of PAP and identify the risk factors associated with rupture. Patients who developed hemoptysis with PAP were collected from January 2019 to December 2022 retrospectively. Clinical data of the demographic characteristics, radiological findings, treatment strategies, and prognosis were collected. A comparative analysis was performed on the characteristics in the ruptured and non-ruptured cases. A total of 58 PAPs were identified in the 50 patients. The most common causes were infection (86%) and cancer (8%). The PAPs were located predominantly in the upper lobes of both lungs, and 57 (99.3%) were distributed in the segmental or subsegmental pulmonary arteries. The median diameter was 6.1(4.3-8.7) mm. A total of 29 PAPs were identified adjacent to pulmonary cavitations, with the median diameter of the cavity being 18.9 (12.4-34.8) mm. Rupture of pseudoaneurysm occurred in 21 cases (42%). Compared to unruptured group, the ruptured group had a significantly higher proportion of massive hemoptysis (57.1% vs. 6.9%, p