Comparing the Effectiveness of Intra-Articular Injection of Bupivacaine, Dexmedetomidine Vs. 0.9% Saline on Pain Control after Arthroscopic Anterior Cruciate Ligament Reconstruction

• Published in: Journal of orthopedic & spine trauma 2020-06, Vol.4 (2)
• Main Authors: Minator Sajjadi, Mohammadreza, Zandi, Reza, Okhovatpour, Mohammad Ali, Jalalpour, Pooyan, Moshari, Mohammadreza
• Format: Article
• Language: English
• Subjects: Intra-Articular Injections; Postoperative Pain; Arthroscopy; Anterior Cruciate Ligament Reconstruction; Bupivacaine; Dexmedetomidine
• ISSN: 2538-2330; 2538-4600
• DOI: 10.18502/jost.v4i2.2957

Background: In different ways, drugs are administered to reduce postoperative analgesia after arthroscopic anterior cruciate ligament (ACL) reconstruction. The purpose of this study is to compare the dexmedetomidine (DEX) intra-articular injection with bupivacaine hydrochloride and sterile 0.9% saline administration following arthroscopic ACL reconstruction.   Methods: Sixty cases who underwent ACL reconstruction were randomly divided into three groups. The first group received intra-articular DEX; the second group received intra-articular bupivacaine, and the final group received intra-articular 0.9% saline. Postoperative pain was measured by Visual Analogue Scale (VAS).   Results: The mean VAS scores at 6 and 24 hours after surgery were lower in the bupivacaine group, compared to the other groups. Pain was more severe in the control group (0.9% saline), with higher VAS scores reported at 1, 6, and 24 hours after surgery.   Conclusions:  Bupivacaine has more significant effects than  DEX  in postoperative pain management after arthroscopic ACL reconstruction.