Impact of multifocal gas-permeable lens designs on short-term choroidal response, axial length, and retinal defocus profile

• Published in: International journal of ophthalmology 2024-02, Vol.17 (2), p.247-256
• Main Authors: Alanazi, Muteb, Caroline, Patrick, Alshamrani, Amane, Liu, Maria
• Format: Article
• Language: English
• Subjects: axial length; choroid; Clinical Research; gas-permeable contact lens; myopia; retinal defocus
• ISSN: 2222-3959; 2227-4898
• DOI: 10.18240/ijo.2024.02.04

To investigate the impact of multifocal gas permeable contact lens (MFGPCL) in various add power and distance/near area allocation on short-term changes of choroidal thickness (ChT), axial length (AL), and retinal defocus profile in young adults. Seventeen young adults (2 males and 15 females; age 23.17±4.48y) were randomly assigned to wear two designs binocularly with a one-week washout period in between. Total of four MFGPCL designs were assessed. All designs were distance-center that varied in two add power (+1.50 and 3.00 D) and/or two distance zone (DZ) diameters (1.50 and 3.00 mm; design A: DZ 1.5/add 3.0, B: DZ 1.5/add 1.5, C: DZ 3.0/add 3.0, D: DZ 3.0/add 1.5). ChT, AL, and peripheral refraction data were collected on each subject at baseline, on days 1 and 7 of MFGPCL daily wear. ChT was assessed in four quadrants using a spectral-domain optical coherence tomography. AL was shortened by -26±44 µm with lens C, -18±27 µm with lens D, -13±29 µm with lens A, and -8±30 µm with lens B (all