Cognitive impairments in patients with low grade gliomas and high grade gliomas

The relationship between brain tumors and cognitive deficits is well established in the literature. However, studies investigating the cognitive status in low and high-grade gliomas patients are scarce, particularly in patients with average or lower educational level. This study aimed at investigati...

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Published in:Arquivos de neuro-psiquiatria 2011-08, Vol.69 (4), p.596-601
Main Authors: Miotto, Eliane C, Junior, Aluizio Silva, Silva, Clemar Corrêa, Cabrera, Hector Navarro, Machado, Melissa A R, Benute, Glaucia R G, Lucia, Mara C S, Scaff, Milberto, Teixeira, Manoel Jacobsen
Format: Article
Language:English
Subjects:
Adult
Brain Neoplasms - complications
Brain Neoplasms - pathology
Cognition Disorders - etiology
Educational Status
funções cognitivas
Glioma - complications
Glioma - pathology
gliomas de alto grau
gliomas de baixo grau
Humans
Middle Aged
Neoplasm Staging
Neuropsychological Tests
NEUROSCIENCES
PSYCHIATRY
tumores cerebrais
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creator Miotto, Eliane C
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Scaff, Milberto
Teixeira, Manoel Jacobsen
description The relationship between brain tumors and cognitive deficits is well established in the literature. However, studies investigating the cognitive status in low and high-grade gliomas patients are scarce, particularly in patients with average or lower educational level. This study aimed at investigating the cognitive functioning in a sample of patients with low and high-grade gliomas before surgical intervention. The low-grade (G1, n=19) and high-grade glioma (G2, n=8) patients underwent a detailed neuropsychological assessment of memory, executive functions, visuo-perceptive and visuo-spatial abilities, intellectual level and language. There was a significant impairment on verbal and visual episodic memory, executive functions including mental flexibility, nominal and categorical verbal fluency and speed of information processing in G2. G1 showed only specific deficits on verbal and visual memory recall, mental flexibility and processing speed. These findings demonstrated different levels of impairments in the executive and memory domains in patients with low and high grade gliomas.
doi_str_mv 10.1590/S0004-282X2011000500005
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subjects Adult
Brain Neoplasms - complications
Brain Neoplasms - pathology
Cognition Disorders - etiology
Educational Status
funções cognitivas
Glioma - complications
Glioma - pathology
gliomas de alto grau
gliomas de baixo grau
Humans
Middle Aged
Neoplasm Staging
Neuropsychological Tests
NEUROSCIENCES
PSYCHIATRY
tumores cerebrais
title Cognitive impairments in patients with low grade gliomas and high grade gliomas
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