The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review

The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamp...

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Bibliographic Details
Published in:Transplantation direct 2021-08, Vol.7 (10), p.e746-e746
Main Authors: Vetrugno, Luigi, Cherchi, Vittorio, Lorenzin, Dario, De Lorenzo, Francesco, Ventin, Marco, Zanini, Victor, Terrosu, Giovanni, Risaliti, Andrea, Baccarani, Umberto, Bove, Tiziana
Format: Article
Language:English
Subjects:
Liver Transplantation
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Summary:The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamping, and reperfusion could also contribute to clot formation. The incidence of intracardiac thrombi formation stands at 4.2%, associated with a mortality rate of 45.5%, and to date, no consensus exists regarding the best way to treat this complication. Intraoperative transesophageal echocardiography is the only effective method for diagnosing intracardiac thrombi formation early, while point-of-care coagulation testing could guide the coagulation management potentially improving patient outcomes.
ISSN:2373-8731
2373-8731
DOI:10.1097/TXD.0000000000001200