The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review

The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamp...

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Published in:Transplantation direct 2021-08, Vol.7 (10), p.e746-e746
Main Authors: Vetrugno, Luigi, Cherchi, Vittorio, Lorenzin, Dario, De Lorenzo, Francesco, Ventin, Marco, Zanini, Victor, Terrosu, Giovanni, Risaliti, Andrea, Baccarani, Umberto, Bove, Tiziana
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Liver Transplantation
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container_issue 10
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container_title Transplantation direct
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creator Vetrugno, Luigi
Cherchi, Vittorio
Lorenzin, Dario
De Lorenzo, Francesco
Ventin, Marco
Zanini, Victor
Terrosu, Giovanni
Risaliti, Andrea
Baccarani, Umberto
Bove, Tiziana
description The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamping, and reperfusion could also contribute to clot formation. The incidence of intracardiac thrombi formation stands at 4.2%, associated with a mortality rate of 45.5%, and to date, no consensus exists regarding the best way to treat this complication. Intraoperative transesophageal echocardiography is the only effective method for diagnosing intracardiac thrombi formation early, while point-of-care coagulation testing could guide the coagulation management potentially improving patient outcomes.
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subjects Liver Transplantation
title The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review
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