Maternal Vitamin D Status and Adverse Birth Outcomes in Children from Rural Western Kenya

Maternal plasma 25-hydroxyvitamin D (25(OH)D) status and its association with pregnancy outcomes in malaria holoendemic regions of sub-Saharan Africa is poorly defined. We examined this association and any potential interaction with malaria and helminth infections in an ongoing pregnancy cohort stud...

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Bibliographic Details
Published in:Nutrients 2016-12, Vol.8 (12), p.794
Main Authors: Toko, Eunice N, Sumba, Odada P, Daud, Ibrahim I, Ogolla, Sidney, Majiwa, Maxwel, Krisher, Jesse T, Ouma, Collins, Dent, Arlene E, Rochford, Rosemary, Mehta, Saurabh
Format: Article
Language:English
Subjects:
25-Hydroxyvitamin D
Adolescent
Adult
Africa
Anthropometry
Birth
Body mass
Body mass index
Causation
Childbirth & labor
Children
Clinical trials
Cord blood
Female
Fetal Blood
Gestational age
Growth Disorders
Health risks
Helminthiasis - complications
Helminthiasis - diagnosis
Humans
Infant, Newborn
Infants
Kenya - epidemiology
Longitudinal Studies
Malaria
Malaria - complications
Malaria - diagnosis
malaria and helminth infections
Male
Maternal Nutritional Physiological Phenomena
maternal vitamin D status
Medical research
Multivariate analysis
Neonates
Plasma
Plasmas (physics)
Pregnancy
Pregnancy Complications, Parasitic
Pregnancy Outcome
pregnancy outcomes
stunting
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D Deficiency
Young Adult
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Summary:Maternal plasma 25-hydroxyvitamin D (25(OH)D) status and its association with pregnancy outcomes in malaria holoendemic regions of sub-Saharan Africa is poorly defined. We examined this association and any potential interaction with malaria and helminth infections in an ongoing pregnancy cohort study in Kenya. The association of maternal plasma 25(OH)D status with pregnancy outcomes and infant anthropometric measurements at birth was determined in a subset of women ( = 63). Binomial and linear regression analyses were used to examine associations between maternal plasma 25(OH)D and adverse pregnancy outcomes. Fifty-one percent of the women had insufficient (
ISSN:2072-6643
2072-6643
DOI:10.3390/nu8120794