Transition-metal-free [3+3] annulation reaction of sulfoxonium ylides with cyclopropenones for the synthesis of 2-pyrones

An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions. A broad range of functional groups were tole...

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Bibliographic Details
Published in:Green synthesis and catalysis 2020-11, Vol.1 (2), p.180-182
Main Authors: He, Maoyao, Chen, Yuncan, Luo, Yi, Li, Jianglian, Lai, Ruizhi, Yang, Zengbao, Wang, Yuerong, Wu, Yong
Format: Article
Language:English
Subjects:
2-Pyrones
[3+3] Annulation
Cyclopropenoens
Sulfoxonium ylides
Transition-metal-free
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Summary:An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions. A broad range of functional groups were tolerant under mild conditions, and a variety of 2-pyrones were obtained in moderate to good yields. An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions. A broad range of functional groups were tolerant under mild conditions, and a variety of 2-pyrones were obtained in moderate to good yields. [Display omitted]
ISSN:2666-5549
2666-5549
DOI:10.1016/j.gresc.2020.10.004