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Daldiniaeschsone A, a Rare Tricyclic Polyketide Having a Chromone Unit Fused to a δ -Lactone and Its Symmetrical Biphenyl Dimer, Daldiniaeschsone B, from an Endophytic Fungus Daldinia eschscholtzii SDBR-CMUNKC745
Daldiniaeschsone A ( ), a rare tricyclic polyketide having a chromone unit fused to a -lactone and its symmetrical 6,6'-biphenyl dimer, daldiniaeschsone B ( ), together with three known compounds ( - ), were isolated from a plant-derived endophytic fungus, SDBR-CMUNKC745. Their structures were...
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Published in: | Journal of fungi (Basel) 2021-05, Vol.7 (5), p.358 |
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creator | Wutthiwong, Natnicha Suthiphasilp, Virayu Pintatum, Aknarin Suwannarach, Nakarin Kumla, Jaturong Lumyong, Saisamorn Maneerat, Tharakorn Charoensup, Rawiwan Cheenpracha, Sarot Limtharakul, Thunwadee Pyne, Stephen G Laphookhieo, Surat |
description | Daldiniaeschsone A (
), a rare tricyclic polyketide having a chromone unit fused to a
-lactone and its symmetrical 6,6'-biphenyl dimer, daldiniaeschsone B (
), together with three known compounds (
-
), were isolated from a plant-derived endophytic fungus,
SDBR-CMUNKC745. Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and HRESIMS. All compounds showed
-glucosidase inhibitory activity with IC
values ranging from 0.16-0.85 mM and compound
was the best
-glucosidase inhibitory activity (IC
= 0.16 mM). |
doi_str_mv | 10.3390/jof7050358 |
format | article |
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), a rare tricyclic polyketide having a chromone unit fused to a
-lactone and its symmetrical 6,6'-biphenyl dimer, daldiniaeschsone B (
), together with three known compounds (
-
), were isolated from a plant-derived endophytic fungus,
SDBR-CMUNKC745. Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and HRESIMS. All compounds showed
-glucosidase inhibitory activity with IC
values ranging from 0.16-0.85 mM and compound
was the best
-glucosidase inhibitory activity (IC
= 0.16 mM).</description><identifier>ISSN: 2309-608X</identifier><identifier>EISSN: 2309-608X</identifier><identifier>DOI: 10.3390/jof7050358</identifier><identifier>PMID: 34063266</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Biphenyl ; biphenyl dimer ; chromone ; Daldinia ; Daldinia eschscholtzii SDBR-CMUNKC745 ; Endophytes ; Fungi ; Metabolites ; Microorganisms ; Natural products ; NMR ; Nuclear magnetic resonance ; Plants ; Ribosomal DNA ; RNA polymerase ; tricyclic polyketide ; α-Glucosidase ; α-glucosidase inhibitory activity</subject><ispartof>Journal of fungi (Basel), 2021-05, Vol.7 (5), p.358</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-2e04036e8696f8bab4a7bb79bca237d971200cc01262b584c97a54704522103a3</citedby><cites>FETCH-LOGICAL-c472t-2e04036e8696f8bab4a7bb79bca237d971200cc01262b584c97a54704522103a3</cites><orcidid>0000-0002-2653-1913 ; 0000-0002-3673-6541 ; 0000-0002-4757-2781 ; 0000-0001-6433-0293 ; 0000-0002-9914-9037 ; 0000-0002-4333-1059</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2532353504/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2532353504?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34063266$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wutthiwong, Natnicha</creatorcontrib><creatorcontrib>Suthiphasilp, Virayu</creatorcontrib><creatorcontrib>Pintatum, Aknarin</creatorcontrib><creatorcontrib>Suwannarach, Nakarin</creatorcontrib><creatorcontrib>Kumla, Jaturong</creatorcontrib><creatorcontrib>Lumyong, Saisamorn</creatorcontrib><creatorcontrib>Maneerat, Tharakorn</creatorcontrib><creatorcontrib>Charoensup, Rawiwan</creatorcontrib><creatorcontrib>Cheenpracha, Sarot</creatorcontrib><creatorcontrib>Limtharakul, Thunwadee</creatorcontrib><creatorcontrib>Pyne, Stephen G</creatorcontrib><creatorcontrib>Laphookhieo, Surat</creatorcontrib><title>Daldiniaeschsone A, a Rare Tricyclic Polyketide Having a Chromone Unit Fused to a δ -Lactone and Its Symmetrical Biphenyl Dimer, Daldiniaeschsone B, from an Endophytic Fungus Daldinia eschscholtzii SDBR-CMUNKC745</title><title>Journal of fungi (Basel)</title><addtitle>J Fungi (Basel)</addtitle><description>Daldiniaeschsone A (
), a rare tricyclic polyketide having a chromone unit fused to a
-lactone and its symmetrical 6,6'-biphenyl dimer, daldiniaeschsone B (
), together with three known compounds (
-
), were isolated from a plant-derived endophytic fungus,
SDBR-CMUNKC745. Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and HRESIMS. All compounds showed
-glucosidase inhibitory activity with IC
values ranging from 0.16-0.85 mM and compound
was the best
-glucosidase inhibitory activity (IC
= 0.16 mM).</description><subject>Biphenyl</subject><subject>biphenyl dimer</subject><subject>chromone</subject><subject>Daldinia</subject><subject>Daldinia eschscholtzii SDBR-CMUNKC745</subject><subject>Endophytes</subject><subject>Fungi</subject><subject>Metabolites</subject><subject>Microorganisms</subject><subject>Natural products</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Plants</subject><subject>Ribosomal DNA</subject><subject>RNA polymerase</subject><subject>tricyclic polyketide</subject><subject>α-Glucosidase</subject><subject>α-glucosidase inhibitory activity</subject><issn>2309-608X</issn><issn>2309-608X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNplkt1u0zAUxyMEYtPYDQ-ALHGDpgb8la8bpLVdt4ryoW2VuItOHKdxSexiJ5PCc-05uON9cNdRNriy5fPzz38fnSB4SfBbxjL8bm2qBEeYRemT4JAynIUxTr8-fbA_CI6dW2OMSZTGWcaeBweM45jROD4Mfk2hKZVWIJ2ondESnY4QoEuwEl1bJQbRKIG-mGb4JjtVSnQBN0qvPDKprWm3F5ZadWjWO1mizvjCz1sULkB02xroEs07h66GtpWd90GDxmpTSz00aKpaaUfovwTjEaq8219GZ7o0m3rofIZZr1e929PoDhe1abofSqGr6fgynHxcfvowSXj0InhWQePk8f16FCxnZ9eTi3Dx-Xw-OV2Egie0C6nEHLNY-rbEVVpAwSEpiiQrBFCWlFlCKMZCYEJjWkQpF1kCEU8wjyglmAE7CuY7b2lgnW-sasEOuQGV3x0Yu8rB-vCNzAkWVcUJk_4dXsiqKIEDJamkpACSYu96v3Nt-qKVpZC6s9A8kj6uaFXnK3OTp4QnPKZe8OZeYM33Xroub5UTsmlAS9O7nEYs9t-maeTR1_-ga9Nb7Vu1pSiLWIS5p052lLDGOSurfRiC8-3w5X-Hz8OvHsbfo39Gjf0G-qjWWw</recordid><startdate>20210502</startdate><enddate>20210502</enddate><creator>Wutthiwong, Natnicha</creator><creator>Suthiphasilp, Virayu</creator><creator>Pintatum, Aknarin</creator><creator>Suwannarach, Nakarin</creator><creator>Kumla, Jaturong</creator><creator>Lumyong, Saisamorn</creator><creator>Maneerat, Tharakorn</creator><creator>Charoensup, Rawiwan</creator><creator>Cheenpracha, Sarot</creator><creator>Limtharakul, Thunwadee</creator><creator>Pyne, Stephen G</creator><creator>Laphookhieo, Surat</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2653-1913</orcidid><orcidid>https://orcid.org/0000-0002-3673-6541</orcidid><orcidid>https://orcid.org/0000-0002-4757-2781</orcidid><orcidid>https://orcid.org/0000-0001-6433-0293</orcidid><orcidid>https://orcid.org/0000-0002-9914-9037</orcidid><orcidid>https://orcid.org/0000-0002-4333-1059</orcidid></search><sort><creationdate>20210502</creationdate><title>Daldiniaeschsone A, a Rare Tricyclic Polyketide Having a Chromone Unit Fused to a δ -Lactone and Its Symmetrical Biphenyl Dimer, Daldiniaeschsone B, from an Endophytic Fungus Daldinia eschscholtzii SDBR-CMUNKC745</title><author>Wutthiwong, Natnicha ; Suthiphasilp, Virayu ; Pintatum, Aknarin ; Suwannarach, Nakarin ; Kumla, Jaturong ; Lumyong, Saisamorn ; Maneerat, Tharakorn ; Charoensup, Rawiwan ; Cheenpracha, Sarot ; Limtharakul, Thunwadee ; Pyne, Stephen G ; Laphookhieo, Surat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-2e04036e8696f8bab4a7bb79bca237d971200cc01262b584c97a54704522103a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biphenyl</topic><topic>biphenyl dimer</topic><topic>chromone</topic><topic>Daldinia</topic><topic>Daldinia eschscholtzii SDBR-CMUNKC745</topic><topic>Endophytes</topic><topic>Fungi</topic><topic>Metabolites</topic><topic>Microorganisms</topic><topic>Natural products</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Plants</topic><topic>Ribosomal DNA</topic><topic>RNA polymerase</topic><topic>tricyclic polyketide</topic><topic>α-Glucosidase</topic><topic>α-glucosidase inhibitory activity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wutthiwong, Natnicha</creatorcontrib><creatorcontrib>Suthiphasilp, Virayu</creatorcontrib><creatorcontrib>Pintatum, Aknarin</creatorcontrib><creatorcontrib>Suwannarach, Nakarin</creatorcontrib><creatorcontrib>Kumla, Jaturong</creatorcontrib><creatorcontrib>Lumyong, Saisamorn</creatorcontrib><creatorcontrib>Maneerat, Tharakorn</creatorcontrib><creatorcontrib>Charoensup, Rawiwan</creatorcontrib><creatorcontrib>Cheenpracha, Sarot</creatorcontrib><creatorcontrib>Limtharakul, Thunwadee</creatorcontrib><creatorcontrib>Pyne, Stephen G</creatorcontrib><creatorcontrib>Laphookhieo, Surat</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals (Open Access)</collection><jtitle>Journal of fungi (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wutthiwong, Natnicha</au><au>Suthiphasilp, Virayu</au><au>Pintatum, Aknarin</au><au>Suwannarach, Nakarin</au><au>Kumla, Jaturong</au><au>Lumyong, Saisamorn</au><au>Maneerat, Tharakorn</au><au>Charoensup, Rawiwan</au><au>Cheenpracha, Sarot</au><au>Limtharakul, Thunwadee</au><au>Pyne, Stephen G</au><au>Laphookhieo, Surat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Daldiniaeschsone A, a Rare Tricyclic Polyketide Having a Chromone Unit Fused to a δ -Lactone and Its Symmetrical Biphenyl Dimer, Daldiniaeschsone B, from an Endophytic Fungus Daldinia eschscholtzii SDBR-CMUNKC745</atitle><jtitle>Journal of fungi (Basel)</jtitle><addtitle>J Fungi (Basel)</addtitle><date>2021-05-02</date><risdate>2021</risdate><volume>7</volume><issue>5</issue><spage>358</spage><pages>358-</pages><issn>2309-608X</issn><eissn>2309-608X</eissn><abstract>Daldiniaeschsone A (
), a rare tricyclic polyketide having a chromone unit fused to a
-lactone and its symmetrical 6,6'-biphenyl dimer, daldiniaeschsone B (
), together with three known compounds (
-
), were isolated from a plant-derived endophytic fungus,
SDBR-CMUNKC745. Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and HRESIMS. All compounds showed
-glucosidase inhibitory activity with IC
values ranging from 0.16-0.85 mM and compound
was the best
-glucosidase inhibitory activity (IC
= 0.16 mM).</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>34063266</pmid><doi>10.3390/jof7050358</doi><orcidid>https://orcid.org/0000-0002-2653-1913</orcidid><orcidid>https://orcid.org/0000-0002-3673-6541</orcidid><orcidid>https://orcid.org/0000-0002-4757-2781</orcidid><orcidid>https://orcid.org/0000-0001-6433-0293</orcidid><orcidid>https://orcid.org/0000-0002-9914-9037</orcidid><orcidid>https://orcid.org/0000-0002-4333-1059</orcidid><oa>free_for_read</oa></addata></record> |
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source | Publicly Available Content Database; PubMed Central |
subjects | Biphenyl biphenyl dimer chromone Daldinia Daldinia eschscholtzii SDBR-CMUNKC745 Endophytes Fungi Metabolites Microorganisms Natural products NMR Nuclear magnetic resonance Plants Ribosomal DNA RNA polymerase tricyclic polyketide α-Glucosidase α-glucosidase inhibitory activity |
title | Daldiniaeschsone A, a Rare Tricyclic Polyketide Having a Chromone Unit Fused to a δ -Lactone and Its Symmetrical Biphenyl Dimer, Daldiniaeschsone B, from an Endophytic Fungus Daldinia eschscholtzii SDBR-CMUNKC745 |
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