Epizootiological investigation of equine herpesvirus type 1 infection among Japanese racehorses before and after the replacement of an inactivated vaccine with a modified live vaccine

Equine herpesvirus type 1 (EHV-1) infection is a major cause of pyrexias in winter among Japanese racehorses. In 2014-2015, the Japan Racing Association (JRA) changed the EHV-1 vaccine from an inactivated vaccine to a live vaccine (both produced by Nisseiken). To evaluate the effect of changing the...

Full description

Saved in:
Bibliographic Details
Published in:BMC veterinary research 2019-08, Vol.15 (1), p.280-280, Article 280
Main Authors: Bannai, Hiroshi, Tsujimura, Koji, Nemoto, Manabu, Ohta, Minoru, Yamanaka, Takashi, Kokado, Hiroshi, Matsumura, Tomio
Format: Article
Language:English
Subjects:
Animals
Antibodies, Viral - blood
Associations
Attenuated vaccines
Diseases
Distribution
EHV-1
Equine herpesvirus diseases
Herpesvirus 1, Equid
Herpesvirus 4, Equid
Horse Diseases - epidemiology
Horse Diseases - prevention & control
Horse Diseases - virology
Horses
Immune response
Inactivated vaccine
Infection
Japan - epidemiology
Live vaccine
Physiological aspects
Prevention
Racehorses
Racing
Seasons
Serologic Tests
Vaccination
Vaccination coverage
Vaccines
Vaccines, Inactivated
Veterinary vaccines
Viral Vaccines - immunology
Virus-neutralizing antibody
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Equine herpesvirus type 1 (EHV-1) infection is a major cause of pyrexias in winter among Japanese racehorses. In 2014-2015, the Japan Racing Association (JRA) changed the EHV-1 vaccine from an inactivated vaccine to a live vaccine (both produced by Nisseiken). To evaluate the effect of changing the vaccines, the capacities of these vaccines to induce virus-neutralizing (VN) antibodies were compared, and an epizootiological investigation of EHV-1 was performed at the JRA Ritto Training Center during epizootic periods from 2010-2011 to 2016-2017. Three-year-old horses that received the first dose of live vaccine showed higher geometric mean (GM) VN titers (205 and 220) than those that received inactivated vaccine (83, P 
ISSN:1746-6148
1746-6148
DOI:10.1186/s12917-019-2036-0