Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6-9.9 mm Pyelectasis

• Published in: Children (Basel) 2023-02, Vol.10 (2), p.407
• Main Authors: Farladansky-Gershnabel, Sivan, Gluska, Hadar, Meyer, Segev, Sharon-Weiner, Maya, Schreiber, Hanoch, Arnon, Shmuel, Markovitch, Ofer
• Format: Article
• Language: English
• Subjects: Amniocentesis; Demographic aspects; Diagnosis; Electronic health records; fetal hydronephrosis; Fetus; Fetuses; Genetic counseling; Gestational age; Growth; Gynecology; Hydronephrosis; Hypertension; long term outcome; Measurement techniques; Medical diagnosis; Medical ethics; Medical examination; Medical records; neonatal outcome; Newborn babies; Obstetrics; Pediatrics; Pregnancy; Pregnant women; pyelectasis; Questionnaires; Ultrasonic imaging; Urogenital system
• ISSN: 2227-9067; 2227-9067
• DOI: 10.3390/children10020407

Pyelectasis, also known as renal pelvic dilatation or hydronephrosis, is frequently found on fetal ultrasound. This study correlated prenatally-detected, moderate pyelectasis with postnatal outcomes. This retrospective, observational study was conducted at a tertiary medical center in Israel. The study group consisted of 54 fetuses with prenatal diagnosis of pyelectasis on ultrasound scan during the second trimester, defined as anteroposterior renal pelvic diameter (APRPD) 6-9.9 mm. Long-term postnatal outcomes and renal-related sequelae were obtained using medical records and telephone-based questionnaires. The control group included 98 cases with APRPD < 6 mm. Results indicate that fetal pyelectasis 6-9.9 mm was more frequent among males (68.5%) than females (51%, = 0.034). We did not find significant correlations between 6-9.9 mm pyelectasis and other anomalies or chromosomal/genetic disorders. Pyelectasis resolved during the pregnancy in 15/54 (27.8%) cases. There was no change in 17/54 (31.5%) and 22/54 (40.7%) progressed to hydronephrosis Among the study group, 25/54 (46.3%) were diagnosed with neonatal hydronephrosis. There were more cases of renal reflux or renal obstruction in the study group compared to the control group 8/54 (14.8%) vs. 1/98 (1.0%), respectively; = 0.002. In conclusion, most cases of 6-9.9 mm pyelectasis remained stable or resolved spontaneously during pregnancy. There was a higher rate of postnatal renal reflux and renal obstruction in this group; however, most did not require surgical intervention.