Virological evidence of the impact of non-pharmaceutical interventions against COVID-19 in Ecuador, a resource-limited setting

Ecuador had substantial COVID-19-mortality during 2020 despite early implementation of non-pharmaceutical interventions (NPIs). Resource-limited settings like Ecuador have high proportions of informal labour which entail high human mobility, questioning efficacy of NPIs. We performed a retrospective...

Full description

Saved in:
Bibliographic Details
Published in:Emerging microbes & infections 2023-12, Vol.12 (2), p.2259001-2259001
Main Authors: Moreira-Soto, Andres, Bruno, Alfredo, de Mora, Doménica, Paez, Michelle, Garces, Jimmy, Wulf, Ben, Sander, Anna-Lena, Olmedo, Maritza, Basantes Mantilla, Maria José, Gonzalez Gonzalez, Manuel, Orlando, Solon Alberto, Salgado Cisneros, Silvia, Zevallos, Juan Carlos, Drexler, Jan Felix
Format: Article
Language:English
Subjects:
Adenoviridae - genetics
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - prevention & control
Ecuador
Ecuador - epidemiology
Humans
Non-pharmaceutical interventions
public health
Resource-Limited Settings
respiratory infections
SARS-CoV-2
SARS-CoV-2 - genetics
Severe acute respiratory syndrome coronavirus 2
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Ecuador had substantial COVID-19-mortality during 2020 despite early implementation of non-pharmaceutical interventions (NPIs). Resource-limited settings like Ecuador have high proportions of informal labour which entail high human mobility, questioning efficacy of NPIs. We performed a retrospective observational study in Ecuador's national reference laboratory for viral respiratory infections during March 2020-February 2021 using stored respiratory specimens from 1950 patients, corresponding to 2.3% of all samples analysed within the Ecuadorian national surveillance system per week. During 2020, detection of SARS-CoV-2 (Pearson correlation;  = -0.74;  = 0.01) and other respiratory viruses (Pearson correlation;  = -0.68;  = 0.02) by real-time RT-PCR correlated negatively with NPIs stringency. Among respiratory viruses, adenoviruses (Fisher's exact-test;  = 0.026), parainfluenzaviruses (  = 0.04), enteroviruses (  
ISSN:2222-1751
2222-1751
DOI:10.1080/22221751.2023.2259001