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Microbiological and immunological characteristics of a lethal pulmonary Aspergillus niger infection in a non-neutropenic patient

Invasive pulmonary aspergillosis is increasingly described in non-neutropenic patients, such as patients with COPD receiving corticosteroids and the critically ill. Here, we present a case of a lethal pulmonary infection in a COPD patient. Immunological tests showed an impaired innate and adaptive i...

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Bibliographic Details
Published in:Medical mycology case reports 2018-09, Vol.21, p.4-7
Main Authors: Workum, Jessica D, de Jong, Suzanne W, Gresnigt, Mark S, Becker, Katharina L, Pickkers, Peter, van de Veerdonk, Frank L, Heijdra, Yvonne F, Kolwijck, Eva
Format: Article
Language:English
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Summary:Invasive pulmonary aspergillosis is increasingly described in non-neutropenic patients, such as patients with COPD receiving corticosteroids and the critically ill. Here, we present a case of a lethal pulmonary infection in a COPD patient. Immunological tests showed an impaired innate and adaptive immune response to . A history of COPD, unresponsiveness to antibiotics and especially a suggestive CT-scan should trigger the clinician to consider diseases caused by
ISSN:2211-7539
2211-7539
DOI:10.1016/j.mmcr.2018.03.002