Segmental ureterectomy for high-risk ureteral carcinoma: a preliminary report

EAU guidelines strongly recommend kidney sparing surgery (KSS) as the primary treatment option for the low-risk UTUC patients. While there are few reports involving the KSS treated for the high-risk counterparts, especially the ureteral resection. To evaluate the effectiveness and safety of the segm...

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Bibliographic Details
Published in:BMC urology 2023-06, Vol.23 (1), p.103-103, Article 103
Main Authors: Wei, Wei, Liu, Junfeng, Wang, Lingdian, Duan, Xiaoyu, Ding, Degang
Format: Article
Language:English
Subjects:
Biopsy
Bladder cancer
Cancer
Carcinoma
Carcinoma, Transitional Cell - pathology
Care and treatment
Cellular biology
Chemotherapy
Complications
High-risk
Hospitals
Humans
Hydronephrosis
Kidney - surgery
Kidney sparing surgery
Medical prognosis
Patients
Postoperative
Prospective Studies
Quality of life
Risk factors
Segmental ureterectomy
Surgery
Survival
Tumors
Ureter - pathology
Ureter - surgery
Ureteral carcinoma
Ureteral Neoplasms - pathology
Urology
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Summary:EAU guidelines strongly recommend kidney sparing surgery (KSS) as the primary treatment option for the low-risk UTUC patients. While there are few reports involving the KSS treated for the high-risk counterparts, especially the ureteral resection. To evaluate the effectiveness and safety of the segmental ureterectomy (SU) for the patients with high-risk ureteral carcinoma. We included 20 patients from May 2017 to December 2021 who underwent segmental ureterectomy (SU) in Henan Provincial People's Hospital. The overall survival (OS) and progression free survival (PFS) were evaluated. Besides, the ECOG scores and postoperative complications were also included. As of December 2022, the mean OS was 62.1months (95%CI:55.6-68.6months) and the mean PFS was 45.0months (95%CI:35.9-54.1months). The median OS and median PFS were not reached. The 3-year OS rate was 70% and the 3-year PFS rate was 50%. The percentage of Clavien I and II complications was 15%. For the selected patients with high-risk ureteral carcinoma, the efficacy and safety of segmental ureterectomy were satisfactory. But we still need to conduct prospective or randomized study to validate the value of SU in patients with high-risk ureteral carcinoma.
ISSN:1471-2490
1471-2490
DOI:10.1186/s12894-023-01265-y