Antimicrobial properties of phenolic acid alkyl esters

The series of phenolic acid (2-, 3-, 4-monohydroxy- and 2,4-, 2,5-dihydroxy) alkyl esters (methyl, ethyl, propyl, and butyl) were prepared, and their antimicrobial activities were determined. The antimicrobial activity against the tested microorganisms Escherichia coli, Pseudomonas aeruginosa, Staph...

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Bibliographic Details
Published in:Czech Journal of Food Sciences 2022-01, Vol.40 (6), p.438-444
Main Authors: Feldeková, Eva, Kosová, Michaela, Berčíková, Markéta, Dragoun, Miroslav, Klojdová, Iveta, Hrádková, Iveta, Šmidrkal, Jan
Format: Article
Language:English
Subjects:
antimicrobial effect
antioxidant properties
parabens
phenolic acid
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Summary:The series of phenolic acid (2-, 3-, 4-monohydroxy- and 2,4-, 2,5-dihydroxy) alkyl esters (methyl, ethyl, propyl, and butyl) were prepared, and their antimicrobial activities were determined. The antimicrobial activity against the tested microorganisms Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Aspergillus brasiliensis was investigated and expressed by minimum inhibitory concentration (MIC) in the range of 1.2-20 mM. The inhibitory activity of higher esters of phenolic acids was found to be higher than that of methyl esters and acids. The minimum inhibitory concentration (MIC) of tested compounds was compared with that of 4-hydroxybenzoic acid and its esters (parabens).
ISSN:1212-1800
1805-9317
DOI:10.17221/135/2022-CJFS